目的用拟合响应曲面法对盐酸丁螺环酮的制备工艺进行改良，并考察其体外释放。
ObjectiveTo optimize the preparation of Buspirone Hydorchloride microspheres by response surface analysis, and investigate the in vitro release.
目的：建立高效液相色谱法测定血浆中盐酸丁螺环酮及其活性代谢物1-嘧啶哌嗪浓度的方法。
Objective: To establish an HPLC method to determine the plasma concentrations of buspirone hydro-chloride (BuHCl) and its active metabolite 1 - pyrimidinyl - piperazine(1 - PP).
目的：建立高效液相色谱法测定血浆中盐酸丁螺环酮及其活性代谢物1-嘧啶哌嗪浓度的方法。
Objective: To establish an HPLC method to determine the plasma concentrations of buspirone hydro-chloride (BuHCl) and its active metabolite 1 - pyrimidinyl - piperazine(1 - PP).
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