至疾病进展时间也有利于DCF组。
目前临床研究存在的主要问题是对于不同患者群体,以及不同疾病进展时间窗的鉴别。
The differentiation of patients with different pathophysiology and during different time windows is important factor related to clinical outcome.
PFS被定义为研究(调查者评估)中经治疗医师所评估的从随即抽样开始到疾病进展或死亡的时间。
PFS was defined as the time from randomisation to disease progression or death as assessed by the treating physicians in the study (investigator-assessed).
在疾病早期,视网膜病没有明显的症状,但是随着时间的推移能进展到一个阶段:眼血管渗漏断裂,甚至致盲。
In its earliest stages, retinopathy often has no overt symptoms but can progress over time to a phase in which the blood vessels of the eye leak and rupture easily, eventually causing blindness.
她说:“这是一种进展缓慢的疾病,大多数情况下,我们有时间、也有机会分辨出哪种治疗策略是最好的。”
"This is a slowly progressing disease and most of the time we have the time and opportunity to determine what's the best [treatment strategy] for our patients," she said.
作为一种折衷措施,一些患者选择短时间服用药物而后停止,以此延缓几年疾病损害的进展。
As a compromise measure, some patients opt to take medication for a short time, staving off for a few years the damage the illness will cause.
回顾一下以前的情况,我们是不是这个原因才一直无法在治疗这些疾病方面取得更大的进展呢?是不是因为我们在某个时间段只能把注意力集中在某一个因素上呢?
When we look back, is this the reason we haven't been able to make more progress on these diseases, by targeting only one element at a time?
回顾一下以前的情况,我们是不是这个原因才一直无法在治疗这些疾病方面取得更大的进展呢?是不是因为我们在某个时间段只能把注意力集中在某一个因素上呢?
When we look back, is this the reason we haven't been able to make more progress on these diseases, by targeting only one element at a time?
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