某些DNA损伤,如烷化剂诱导的次级损伤(无碱基位损伤)可作为诱导性易错修复功能的靶损伤。
Certain DNA lesions, apurinic sites, the secondary DNA lesions induced by alkylating agents, for example, are the proper substrates of the inducible error-prone repair activity.
亚硝基脲的抗癌与致癌机理是非常接近的,都能够使DNA碱基发生烷化,进一步形成DNA股间交联。
The anticancer mechanism of nitrosoureas is very similar to the carcinogenic mechanism, both of them can alkylate DNA bases and form DNA cross-linking further.
亚硝基脲的抗癌与致癌机理是非常接近的,都能够使DNA碱基发生烷化,进一步形成DNA股间交联。
The anticancer mechanism of nitrosoureas is very similar to the carcinogenic mechanism, both of them can alkylate DNA bases and form DNA cross-linking further.
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