雄激素拮抗剂氟他胺也能够部分抑制(5 0 %)睾酮对细胞内AR蛋白水平的上调作用。
Furthermore, androgen up-regulation of intracellular ar protein was partially inhibited (50%) by nonsteroidal androgen antagonist, flutamide.
结论MCF-7乳腺癌细胞株中雄激素受体存在自动调节，氟他胺和羟基氟他胺上调雄激素受体的表达。
CONCLUSIONS Androgen can autoregulate the expression of androgen receptor in MCF-7 breast cancer cell line. Flutamide and hydroxyflutamide up regulate the expression of androgen receptor.
目的：建立分离测定氨苯蝶啶、阿米洛利、呋塞米、布美他尼、氟噻嗪、吲达帕胺、苄氟噻嗪等7种利尿药的新方法。
Objective: To set up a new method for the separation of 7 diuretics: triamterene, amiloride, furosemide, bumetanide, chlorothiazide, indapamide and bendroflumethiazide.
目的：建立分离测定氨苯蝶啶、阿米洛利、呋塞米、布美他尼、氟噻嗪、吲达帕胺、苄氟噻嗪等7种利尿药的新方法。
Objective: To set up a new method for the separation of 7 diuretics: triamterene, amiloride, furosemide, bumetanide, chlorothiazide, indapamide and bendroflumethiazide.
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