• 结论:低温对脑缺血的保护机制之一可能是降低了神经细胞的兴奋毒性指数。

    Conclusion: the neuroprotective effect of hypothermia on cerebral ischemia may reside, in part, in its ability to decrease extracellular excitotoxic indexes.

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  • 通过构效关系研究,发现某些电子结构指数与毒性之间存在较好的相关关系。

    It was found that there are remarkable correlation relationships between some indices of electronic structure and the toxicity by the studies of structure-activity relationship.

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  • 选用分子连接性指数法对毒性数据进行定量结构活性关系(QSAR)研究。

    The quantitative structure-activity relationship (QSAR) models were developed for the toxicity by using the molecular connectivity index method.

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  • S72014对小白鼠的毒性比硝唑咪低达10倍,其化疗指数则高达硝唑咪的3.5倍。

    S72014 was 10 times less toxic than niridazole and had a chemotherapeutic index 3.5 times as great.

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  • 亚硝胺类化合物的结构与毒性之间存在着一定的相互关系。用诱导效应指数I作为结构的特征键参数可以得到烷基亚硝安的结构与毒性的定量关系。

    By using the inductive effect index I as a characteristic bond-parameter, a formula is given describing the relation between the structure of N-nitrosamines and its acute toxicity.

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  • 许多抗肿瘤药具有治疗指数低的特征,其药代动力学在病人个体间存在较大的差异,而且具有较高毒性。

    Most anticancer drugs are characterized by a narrow therapeutic index, wide inter patient variability of pharmacokinetic parameters and high toxicity.

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  • 采用四甲基噻唑兰(MTT)比色法测细胞毒性作用,并计算细胞的存活率利治疗指数(TI)。

    MTT method was used to evaluate the cytotoxicity, and the cell viability and therapeutic index (ti) was calculated.

    youdao

  • 采用四甲基噻唑兰(MTT)比色法测细胞毒性作用,并计算细胞的存活率利治疗指数(TI)。

    MTT method was used to evaluate the cytotoxicity, and the cell viability and therapeutic index (ti) was calculated.

    youdao

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