核心蛋白在一个特定基因型的方式和IRS1退化。
Core protein and IRS1 degradation in a genotype - specific manner.
目的:探讨核心蛋白聚糖(DCN)在乳腺癌中的表达。
Objective: To investigate the expression of decorin (DCN) in breast carcinoma.
硫酸乙酰肝素是一种结合在核心蛋白上的带负电荷的长直链多糖。
Heparan sulfates are long, unbranched, negatively charged polysaccharides that are bound to core proteins.
目的利用杆状病毒表达载体系统制备重组乙型肝炎病毒核心蛋白。
Objective To produce recombinant HBcAg in insect cells by Baculovirus expression vector system.
目的构建土拨鼠肝炎病毒核心蛋白质粒并进行原核表达、抗体制备。
Objective To construct the prokaryotic expression plasmid expressing woodchuck hepatitis virus core antigen (WHcAg) and prepare polyclonal antibodies.
核心蛋白聚糖的代谢异常或结构改变与许多疾病的病理过程有密切关系。
Its metabolism disorders or structural changes have close relationship with pathologic process of many diseases.
结果:综述了丙型肝炎病毒核心蛋白t、b细胞表位及对细胞周期的影响。
Results: There are some t and B cell epitopes on HCV core protein, and HCV core protein can affect cell cycle.
而GBM内主要的HS蛋白多糖核心蛋白—集聚蛋白(Agrin)染色没有变化。
Staining for agrin, the major HS proteoglycan core protein in the GBM, was unaltered.
目的:研究抑癌基因PTEN在人肝细胞肝癌中的表达及其与HCV核心蛋白间的关系。
Objective: To study the relationship between PTEN expression and HCV core protein in hepatocellular carcinoma (HCC).
修饰的乙肝核心蛋白或其聚集的核衣壳蛋白颗粒可悬垂连接到半抗原上以形成一修饰的核衣壳偶联物。
The modified hepatitis B core protein or its aggregated nucleocapsid protein particles can be pendently linked to a hapten to form a modified nucleocapsid conjugate.
结论利用酵母双杂交Gal4系统3研究与HCV核心蛋白相互作用的蛋白,证实了HCV核心蛋白无自激活功能。
CONCLUSION: Yeast two-hybrid GAL4 system 3 can be utilized to fish HCV core region-interacting protein. HCV core protein does not have self-activating function.
目的:构建丙型肝炎病毒(HCV)全长及3种不同缺失突变的核心蛋白基因的原核表达载体,并在大肠杆菌中表达。
AIM: to construct the recombinant plasmids expressing full-length HCV core protein gene and 3 different deletion mutated hepatitis core protein genes and to express them in E. coli.
目的:比较B,C两种基因型HBV核心蛋白在促进肝细胞凋亡方面的差异,以期初步阐述HBV基因型与临床关系的发病机制。
AIM: To compare the proapoptosis effect of hepatitis B virus (HBV) genotype B and C core proteins on liver cells, and explore the pathogenesis of HBV infection with different genotypes.
了解hCV核心蛋白在诱发肝脂肪变性中的分子学机制,对丙型肝炎相关性脂肪肝的病因学,预防和治疗等方面具有极大的促进作用。
Understanding the molecule mechanisms of HCV core protein induction hepatic steatosis may contribute to elucidate the etiology, prevention and treatment of HCV hepatic diseases.
组蛋白 H3与H2A,H2B,H4 共同构成了真核生物核小体的八聚体核心。
Histone H3 along with H2A, H2B, and H4 form the eukaryotic nucleosome octamer core.
但是弄清蛋白质折叠的规则一直是生物学的核心问题之一。
But understanding the rules of protein folding remains one of biology's central problems.
数据分析是蛋白质组研究的核心。
这是一张附加在人造纤维上内皮细胞的照片,它用微管的、F -肌动蛋白和核心来染色。
This is an image of an endothelial cell attached to synthetic microfibers, stained with microtubules, F-actin and nuclei.
科学家发表在《基因组研究》杂志的文章说,锁钥机制的核心分子是一个叫做CTCF的蛋白。
The molecule at the heart of the lock-and-key mechanism is a protein called CTCF, say the scientists in a paper published in the journal Genome Research.
研究人员分析了突变蛋白的功能,发现它是该蛋白激发激酶作用的部分,是酶缺矢功能的核心环节。
The researchers analyzed the function of the mutant proteins, establishing that it was the "triggering" kinase segment of the protein that was central to the enzyme's defective function.
令人惊讶的是,我们发现一个分泌蛋白,IGFBP7在BRAFV600E介导的衰老和凋亡中发挥核心作用。
Surprisingly, we find a secreted protein, IGFBP7, has a central role in BRAFV600E-mediated senescence and apoptosis.
这意味着它由一种蛋白质核心颗粒病毒基因组内有它的形式双链脱氧核糖核酸。
Meaning that it consists of a proteinaceous core particle that has the viral genome inside of it in the form of double stranded DNA.
组蛋白是染色质的核心,其尾部共价修饰在基因表达调控中有重要作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
目前,配体-复合物理论的核心内容是配体与蛋白结合启动特定的生物作用以及配体如何与蛋白一对一的结合。
Currently, the theory about ligands - compounds that bind to proteins and trigger a specific biological action - and how they bind to proteins runs along the lines of a one person-one vote paradigm.
蛋白质组学研究的核心技术之一是分离分析方法。
The separation and analytical technique is one of the core technologies in proteomic studies.
核心过程的表观遗传的产业包括DNA甲基化、组蛋白改性、核小体重建、核染色质动力学和互动子都存在。
Core processes of epigenetic inheritance include DNA methylation, histone modification, nucleosome remodeling, nuclear dynamics and chromatin interaction with non-coding RNAs.
细胞周期调控机制的核心是一组蛋白激酶。
The core of cell cycle regulation and control mechanism are relative to a group of protein kinase.
相对较大的荧光蛋白探针会干扰肌动蛋白的功能和运动,但是通过小探针标记的肌动蛋白分子能够通过细胞甚至进入核心。
The relatively larger GFP interferes with the function and mobility of actin, but actin molecules tagged with the smaller PRIME probes were able to move throughout the cell and even enter the nucleus.
骨骼肌不仅是代谢主要的器官,同时也是最大的蛋白储存库,此外,骨骼肌在某些病理情况下的氮平衡中扮演着核心的角色。
It is not only the major site of metabolic activity but it is also the largest protein reservoir, and playing a central role in nitrogen flow during some disease states.
骨骼肌不仅是代谢主要的器官,同时也是最大的蛋白储存库,此外,骨骼肌在某些病理情况下的氮平衡中扮演着核心的角色。
It is not only the major site of metabolic activity but it is also the largest protein reservoir, and playing a central role in nitrogen flow during some disease states.
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