以2,3 -二氯苯胺为原料,经3步亲核取代反应合成了阿立哌唑。3步反应的收率分别为83%,91%和90%;总收率68%。
Aripiprazole in overall yield of 68% was synthesized from 2, 3-dichloroaniline by a three-step nucleophilic substitution reaction in yield of 83%, 91% and 90%, respectively.
氨基- 1,2,4 -三唑与苦基氯的亲核取代反应动力学研究。
Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.
氨基- 1,2,4 -三唑与苦基氯的亲核取代反应动力学研究。
Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.
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