目的建立一种快速、体外筛选晚期糖基化终产物(age)交联结构裂解剂的方法。
AIM To establish a rapid method for screening advanced glycation end product (AGE) cross links breaker in vitro.
方法:应用竞争性el IS A法检测慢性肾功能衰竭患者(非血液透析组及血液透析组)血清晚期糖基化终产物水平。
Methods The serum advanced glycosylation end products in patients with chronic renal failure (hemodialysis group and non-hemodialysis group) were measured with competitive ELISA.
目的研究晚期糖基化终产物(AGE)修饰蛋白对人内皮细胞分泌单核细胞趋化蛋白1(MCP 1)的影响及其作用的信号传导途径。
Objective To investigate the effects of advanced glycation end products (AGE) on secretion of monocyte chemoattractant protein-1(MCP-1) by human endothelial cells and its signal transduction pathway.
总之,食物中的晚期糖基化终产物含量越高,血液中的晚期糖基化终产物水平就越高,C反应蛋白和其他一些炎症标记分子的水平就越高。
Overall, the higher the participants' consumption of foods rich in AGEs, the higher their blood levels of AGEs and the higher their levels of C-reactive protein and other biomarkers of inflammation.
这项研究包括172名健康者,年龄在18到45岁之间和60到80岁之间,研究发现在受试者中,64岁及以上的人晚期糖基化终产物的含量比45岁以及以下的人高35%。
The study of 172 healthy men and women, ages 18-45 and ages 60-80, found that AGE levels were 35 percent higher in participants age 64 and older than in those younger than age 45.
这项研究包括172名健康者,年龄在18到45岁之间和60到80岁之间,研究发现在受试者中,64岁及以上的人晚期糖基化终产物的含量比45岁以及以下的人高35%。
The study of 172 healthy men and women, ages 18-45 and ages 60-80, found that AGE levels were 35 percent higher in participants age 64 and older than in those younger than age 45.
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