应用于抗肿瘤新药筛选；
目前该模型已用于以adrb3为靶点减肥新药筛选。
Currently, the model has been used for screening novel human ADRB3 agonists.
该活性片段经国家新药筛选中心确证有抑制单胺氧化酶的效果，具有潜在的抗衰老作用。
National Center for Drug Screening confirmed that the bioactive fraction was reliably inhibitory to monoamine oxidase and possessed potential anti-ageing effect.
最近的研究还发现，斑马鱼不仅用于新药筛选，还可用于药物结构的优化。本文重点介绍斑马鱼在新药发现中的应用。
This review summarizes recent progress in drug discovery including identification and validation of novel drug targets, and screening for new therapeutic compounds.
该文简要介绍了SPR生物传感器的基本原理，重点评述了其在新药筛选和药物作用机制方面的研究进展，并对其前景进行了展望。
In this review, the basic principle of SPR biosensor was introduced briefly, and its application in drug research including drug screening and the mechanism of drug action was also reviewed in detail.
组合化学与大规模筛选相结合用于识别与治疗用靶蛋白结合的化合物即潜在新药。
Combinatorial chemistry is used in tandem with high-throughput screening to identify compounds that bind to a therapeutic target protein and are thus potential new drugs.
用小型的、自动机技术针对靶蛋白、细胞或组织筛选大量化合物文库以识别潜在新药。
The use of miniaturized, robotics-based technology to screen large compound libraries against an isolated target protein, cell or tissue in order to identify binders that may be potential new drugs.
结论这一模型有助于筛选抗黏膜高分泌的新药和研究气道黏膜高分泌的病理机制。
Conclusion This model helps to screen the new drugs for mucus hypersecretion and research on the pathological mechanism of airway mucus hypersecretion.
建立合理的药动学筛选模型不仅可以降低新药开发的成本，并且可以在新药研究早期对其作出正确的评价。
Establishing rational pharmacokinetic screening models can not only decrease the cost of finding new drugs, but also give a correct evaluation at the beginning of drug research.
同时，它还是疾病诊断和治疗的重大方法学突破，也是新药开发筛选的新方法。
At the same time, it's a great breakthrough of methodology in diagnosis and therapy of disease, also a new way to exploit and filtrate the medicine.
虚拟筛选节省了大部分化合物合成或购买以及实际生物测试的时间和花费，大大加快了新药研发的过程并降低了成本。
Virtual screening has not only speed the process of new drug research and development, but also reduces products costs gristly.
研究CYP450对新药设计、筛选、评价及优化有重要意义。
Research on genetic polymorphism of CYP450s is significant to drug design, screening, evaluation and optimization.
它利用各种计算方法对化合物数据库进行“筛选”，可以大大减少工作量与成本，加快新药发现步伐。
It employs different computing methods to screen in the chemical compound database greatly reducing efforts and cost and increasing the pace of drug discovery.
用表面呈现技术构建文库并从中筛选新的生物活性物质，如抗体、受体或疫苗，已成为研究生物新药的捷径之一。
Screening novel products with bioactivities, such as antibodies, receptors and vaccines has become a convenient way to develop novel biopharmaceuticals.
用分子细胞生物学、生物化学、遗传学等手段研究肿瘤细胞内的信号传导通路与肿瘤发生机理；筛选肿瘤治疗特异性靶标与新药开发。
Using molecular cell biology, biochemistry, genetics and other approaches to study the signal transduction pathways in cancers and establish tumor targeting strategy for drug development.
目的进行竹黄菌的人工培养，并对其发酵液的抗菌活性进行研究以筛选天然抗菌新药。
OBJECTIVE to investigate into the antibiotic activity of extract of fermented bamboo parasitic fungus cultivated artificially so as to develop new natural antibiotics.
虚拟筛选过程将产生大量复杂的中间数据，对这些数据的有效管理是下阶段新药研发的基础。
A large amount of complex data will be produced in virtual screening and the effective management of these data is the basis of next research in drug discovery.
针对天蚕茧解舒难的问题，根据人工饲育天蚕茧的特性，采用煮茧前热湿处理，并筛选出煮茧新药剂，确立了天蚕茧解舒新工艺。
With a view to tackling the tough problem in Yamamai cocoon reeling, a new reeling process is established by wet heat treatment prior to cocoon cooking and selection of new cocoon cooking chemicals.
该药物的筛选方法能够减少开发新药物的成本和克服单一药物 施用的不足等。
The screening method can reduce the cost for exploiting new pharmaceuticals and overcome the insufficiency when using a single pharmaceutical etc.
这些工作为利用果蝇模型快速筛选治疗结核病的新药物靶标和药物先导物提供了思路。
These might be helpful to the identification of novel anti-tuberculosis drug targets and lead discovery via the facile Drosophila model.
花生四烯酸代谢产物白三烯B_4与炎症及过敏反应中白细胞的各种活动密切相关。筛选有效的白三烯B_4抑制荆可为临床提供抗炎抗过敏反应的一代新药。
LTB4 is one of the metabolites of arachidonic acid via 5-Hpoxygenase pathway. lt is a potent inflammatory mediator and is related to actions of leukocytes in hypersensitive reactions.
花生四烯酸代谢产物白三烯B_4与炎症及过敏反应中白细胞的各种活动密切相关。筛选有效的白三烯B_4抑制荆可为临床提供抗炎抗过敏反应的一代新药。
LTB4 is one of the metabolites of arachidonic acid via 5-Hpoxygenase pathway. lt is a potent inflammatory mediator and is related to actions of leukocytes in hypersensitive reactions.
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