目的：探讨hoxa11基因顺式作用元件是否存在启动子及孕激素应答元件序列。
Objective: To explore the promoter position and existence of progesterone response element in HOXA11 gene cis-acting element.
酵母单杂交实验表明它能与ABA应答元件（ABRE）结合，而ABRE元件广泛存在于胁迫诱导基因中。
Yeast one-hybrid assay demonstrated it can bind to ABA-responsive element (ABRE), which was found in most stress-induced genes.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上，从而在转录水平上调节基因的表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
目的：研究雷洛昔芬对血管内皮细胞雌激素应答元件(ERE)转录活性的影响与雌激素受体(er)亚型的关系。
Objective: to investigate the effect of Raloxifene on the estrogen responsive element (ERE) transcription activity and its relationship with estrogen receptor subtypes in vascular endothelial cells.
目的：研究雷洛昔芬对血管内皮细胞雌激素应答元件(ERE)转录活性的影响与雌激素受体(er)亚型的关系。
Objective: to investigate the effect of Raloxifene on the estrogen responsive element (ERE) transcription activity and its relationship with estrogen receptor subtypes in vascular endothelial cells.
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