目的是探讨原发性膜增殖性肾小球肾炎（MPGN）的临床与病理特征。
The objective is to assess the clinical and pathological features of primary membranoproliferative glomerulonephritis (MPGN).
膜性肾病特征是肾小球基底膜(上左图——基膜)的增厚。
Membranous nephropathy. This kidney disorder is the result of thickening membranes within the glomeruli.
膜性肾病特征是肾小球基底膜(上左图——基膜)的增厚。
Membranous nephropathy.This kidney disorder is the result of thickening membranes within the glomeruli.
电镜图示，由于免疫复合物沉积在肾小球毛细血管袢中，使基底膜增厚（箭头）。
The thickened basement membrane (arrow) that results from immune complex deposition in the glomerular capillary loop is prominent in this electron micrograph.
相关分析表明，肾组织et与尿蛋白排泄量、基底膜厚度呈正相关，与肾小球滤过率(GFR)呈负相关。
Related analysis demonstrated that the levels of ET in renal tissue were positively associated with urinary protein contents, basement membrane thickness, negatively with GFR.
方法：用图像分析系统测量多柔比星肾病大鼠肾小球面积、系膜区面积和系膜细胞数。
Methods: the glomerular areas, mesangial areas and the number of mesangial cells of Doxorubicin nephropathy in rats were measured by quantitative morphometry study.
目的研究氯通道阻滞剂对肾小球系膜细胞增殖的作用。
Aim To investigate effects of chloride channel blockers on proliferation of mesangial cells.
目的观察缓激肽（BK）对高糖浓度下肾小球系膜细胞增殖和细胞外基质分泌的影响。
Objective To observe the effect of bradykinin(BK) on kidney mesangial cell multiplication and extracellular matrix secretion under high glucose environment.
结论ALD通过调控细胞周期抑制肾小球系膜细胞增殖。
Conclusion ALD inhibits the proliferation of rat mesangial cells by regulating cell cycle.
目的探讨醛固酮对大鼠肾小球系膜细胞结缔组织生长因子基因表达的影响。
To evaluate the effect of aldosterone on connective tissue growth factor mRNA expression in cultured rat mesangial cells.
结论一定浓度的苦参素可以抑制肾小球纤维化，保护肾小球系膜细胞，而对系膜细胞的表型转化无明显作用。
Conclusion Certain concentration of oxymatrine can inhibit kidney fibrosis and protect mesangial cells, but have no effect on the phenotype of mesangial cells.
结论：四黄汤对糖尿病大鼠肾小球系膜及基底膜增生具有一定抑制作用。
Conclusion: Sihuang Soup helds some inhibitory effect on hyperplasia of mesangium and basement of rats with diabetes.
目的：探讨尼卡地平对大鼠肾小球系膜细胞凋亡的影响及其分子机理。
Objective:To explore the effects of nicardipine on apoptosis of rat mesangial cells and its molecular mechanisms.
目的研究醛固酮(ald)及其受体拮抗剂螺内酯(SPI)对大鼠肾小球系膜细胞增殖和细胞周期的影响。
Aim to evaluate the effects of aldosterone (ald) and spironolactone (spi, one of the aldosterone receptor antagonists) on proliferation and cell cycle phase of cultured rat mesangial cells in vitro.
电镜下膜增生性肾小球肾炎ii型，基底膜有电子致密物沉积。
This electron micrograph demonstrates the dense deposits in the basement membrane of MPGN type II.
目的：探讨中药肾康注射液对脂多糖诱导肾小球系膜细胞增殖的影响。
Objective: To study the effect of Shenkang injection on the proliferation of human mesangial cell induced by LPS.
目的了解抗肾小球基底膜(GBM)抗体相关疾病的不同临床类型及其临床病理特点。
Objective To investigate the clinical and pathological characteristics of anti glomerular basement membrane (GBM) antibody associated diseases with different clinical patterns.
目的探讨人肾小球系膜细胞脂蛋白脂酶（LPL）的表达情况以及极低密度脂蛋白（VLDL）对其表达的影响。
Objective To study the expression of lipoprotein lipase(LPL) in human glomerular mesangial cells and the effect of very low-density lipoprotein(VLDL) on the expression of LPL.
用阳离子化牛血清白蛋白复制家兔膜性肾小球肾炎的动物模型，并用中药肾炎益气液进行治疗。
The cationic bovine serum albumin (c-BSA) was used for duplicating experimental animal models of membranous glomerulonephritis and Shenyan Yiqi Decoction was used for treatment.
对小球形液膜内气体经由细管流向大球形液膜内过程中，球形液膜的动态特性做了理论模拟与实验研究。
A demonstration is designed to verify the dynamic characteristics of spherical liquid film as the gas in a small spherical liquid film flows to the big one through a tubule.
病理表现为系膜基质增多，肾小球基底膜上皮下透明物质积聚以及毛细血管袢与包氏囊粘连等改变。
The pathological character shows that messegium increased, transparency material of the glomerulus basement membrane epithelium accumulates, capillary and capsular adheres.
目的探讨决定抗肾小球基底膜(GBM)抗体相关疾病预后的可能因素。
Objective to identify the prognostic factors of patients with anti-glomerular basement membrane (GBM) antibody associated diseases.
目的：探讨血小板活化因子(PAF)对肾小球系膜细胞(GMC)合成前列腺素e2 (PGE2)的影响及其意义。
OBJECTIVE to explore the effect and significance of platelet activating factor (PAF) on prostaglandin E2 (PGE2) synthesis in rat glomerular mesangial cell (GMC) in culture.
目的研究血小板衍生生长因子bb (PDGF - BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
Objective to investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB (PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.
结论护肾固精方治疗系膜增殖性肾炎等肾小球疾病的作用机理之一，可能与抑制MC增殖和促其细胞凋亡有关。
Conclusion One of action mechanism of HSGJF treating mesangial proliferative nephritis and other renal glomerular diseases is to inhibit MC proliferation and promote apoptosis.
因此TGP可以保护高糖诱导的肾小球系膜细胞氧化应激损伤。
Therefore we conclude that TGP could protect mesangial cells against oxidative stress induced by high glucose.
目的探讨“延肾胶囊”对残肾肾小球系膜细胞凋亡及其细胞外基质代谢的影响。
Objective To elucidate the effect of Yan-Shen Capsule on glomerular mesangial cell apoptosis and extracellular matrix metabolism of remnant kidney.
纵观过去30多年时间，II型膜增生性肾小球肾炎与致密物沉积病两者的病因学和发病机理已经表露出了显著差别。
Over the last 30 years, marked differences in etiology and pathogenesis between type II membranoproliferative glomerulonephritis and dense deposit disease have become apparent.
因此，抑制肾小球系膜细胞增殖是防治肾小球硬化的重要措施。
It is concluded that it is a key to treat the glomerular sclerosis by inhibiting the proliferation of mesangial cells.
提示尿nag活性测定可作为间接反映肾小球滤过膜功能、筛查糖尿病早期肾病的一项敏感指标。
All these suggested that the determination of urinary NAG activity can be used as a sensitive indicator predicting early diabetic nephropathy.
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