目的：考察不同厂家的盐酸小檗碱片的溶出度，为控制药品质量提供依据。
Objective: to determine the dissolution of berberine hydrochloride tablets produced by the different factories was determined in order to provide the basis for appraisal of the medicine quality.
以盐酸小檗碱的含量和得膏率为考查指标，采用正交试验法对提取工艺进行优选。
MethodsThe content of berberine hydrochloride and the yield of extract were used for the indicators, and the orthogonal experiment was adopted for the optimization.
结果黄连水提液和小檗碱对菌体均有抑菌效果，黄连水提液的抑菌效果尤为明显；
ResultsThe aqueous extract solution and berberine had effect of growth inhibition on bacteria, and the antibacterial effect of aqueous extract solution was very obvious;
该工艺盐酸小檗碱提取率较高，有较好的稳定性，且工艺简便经济，适合于生产。
ConclusionThis process has higher extraction rate of berberine hydrochloride and has good stability, which is simple and economic, and is suitable for industrial production.
目的研究压力超负荷致心肌肥厚模型大鼠心脏结构的变化特点及小檗碱对此的干预作用。
Objective To study the characteristics of heart structure changes in rat model with hypertrophic cardiomyopathy (HCM) induced by pressure-overload, and the interference of berberine.
新疆的黑果小檗分布广，资源丰富，是优良的野生资源植物，具有较大的开发利用潜力。
Berberis heteropoda in Xinjiang distribute widely, and the resource is abundant. It is a kind of good wild resources plant and has great potential to be developed.
目的：研究小檗碱对高转移性人巨细胞肺癌PG细胞侵袭和迁移的作用并探讨其作用机制。
AIM:To study the effect of berberine(Ber) on invasion and migration of PG cells from a high metastatic human giant lung carcinoma cell line and to explore its mechanism.
本发明涉及一种用于治疗畜禽敏感菌感染的预混剂，包括硫酸新霉素、盐酸小檗碱和辅 料。
The invention relates to a premix for the treatment of sensitive bacteria infection of fowl and livestock containing neomycinsulphat, berberine hydrochloride and accessories.
为了建立盐酸小檗碱片新的含量测定方法，采用分光光度法与HPLC法，同时与碘量法对比。
To make a new method of content assay of the berberine hydrochloride tablet, take spectrophotometric method and HPLC assay and compare with iodometric method at the same time.
目的观察小檗碱对胃溃疡小鼠胃黏膜血管活性物质一氧化氮，一氧化氮合酶以及内皮素含量的影响。
ObjectiveTo observe the influence of berberine on vasoactive substances of gastric mucous coat, including nitric oxide, nitric oxide synthase and endothelin in mice with gastric ulcer.
其中盐酸小檗碱的MIC值定义为与生长对照相比，肉眼观察出现80%生长抑制的最低药物浓度。
The MIC value of Berberine was defined as that growth compared with the naked eye control showing appear 80% growth inhibition of the minimum drug concentration.
结果小檗碱凝胶剂不同剂量组对二甲苯所致的小鼠耳肿胀与对照比较无显著性的差异（P>0.05）；
Results:The effect on the ear tumefacient rat with xylene by different dosage of Berberine flocculant had no significant differentiae to the comparison(P>0. 05);
目的比较浸渍法、一般回流提取法、连续回流法、超声提取法、复合方法提取黄连中盐酸小檗碱的提取率。
Objective to compare impregnation, extraction back to normal, continuous circumfluence, ultrasonic extraction, complex method of extraction of berberine hydrochloride in the Chinese extraction rate.
盐酸小檗胺静注和腹腔注射都可延长小白鼠两侧颈总动脉结扎后的生存时间，其作用与静注维拉帕米类似。
The results showed that berbamine significantly prolonged survival time in mice treated by ligation of bilateral carotid arteries and the oxygen consumption in normal mice was decreased by the drug.
对从黄连中提取小檗碱成分的超声技术工艺进行了系统的实验研究，给出了超声提取小檗碱的最佳工艺参数。
The techniques of extracting berberine from rhizoma of Coptis chinese by ultrasound are studied by experiment systematically. The OPtimum parameters for extraction berberine are proposed.
体外兔脑微管蛋白聚合-解聚分析表明，药根碱和小檗碱均能抑制微管蛋白的聚合，且药根碱作用强于小檗碱。
Rabbit brain in vitro tubulin polymerization-depolymerization showed that jatrorrhizine and berberine can inhibit tubulin polymerization, and jatrorrhizine are stronger than that of berberine.
结论：小檗碱对PG细胞增殖具有抑制作用，后者可能与调节细胞内活性氧自由基产生从而影响细胞周期进程有关。
CONCLUSION: Berberine has an inhibitory effect on the proliferation of PG cells, and these effect may be carried out by regulating the production of intracellular ROS and the process of cell cycle.
实验表明，小檗碱未影响胰岛素的分泌与释放，也未影响肝细胞膜胰岛素受体的数目与亲和力，小檗碱的作用可能为受体后效应。
Experiments showed that berberine neither affected insulin secretion or release, nor affected the capacity and affinity of insulin receptor of liver membrane.
本发明涉及一种具有治疗2型糖尿病及防治2型糖尿病慢性并发症作用的药物组合物，该组合物由含一定比例的芒果苷与小檗碱组成。
A drug composition for treating type 2 diabetes and diabetic chronicity complications is disclosed. The composition is composed of mangiferin and berberine in a certain ratio.
摘要 ： 目的：研究大叶小檗75%乙醇提取物及总生物碱对H22荷瘤小鼠肿瘤的抑制作用，为进一步开发其药用价值提供依据。
Abstract : To study the amur barberry root 75% ethanol extract and total alkaloid of H22 mice tumorburdened bone tumor inhibition and provide the basis for further development of its medical value.
西雅图还是俄勒冈葡萄的故乡——它同小檗的亲缘关系比它同真正的葡萄的关系更近些——还有英国常春藤。这是一种入侵藤本，西雅图一带的手艺人用来编织篮子。
Seattle is also home to the Oregon grape — more closely related to the barberry than an actual grape — and English ivy, an invasive vine that Seattle-area crafting groups weave into baskets.
西雅图还是俄勒冈葡萄的故乡——它同小檗的亲缘关系比它同真正的葡萄的关系更近些——还有英国常春藤。这是一种入侵藤本，西雅图一带的手艺人用来编织篮子。
Seattle is also home to the Oregon grape — more closely related to the barberry than an actual grape — and English ivy, an invasive vine that Seattle-area crafting groups weave into baskets.
应用推荐