目的探讨骨骼肌失神经的退变和再生。
Objective To study the degeneration and regeneration of skeletal muscle after denervation.
组(对照组)：肱二头肌完全失神经支配。
Group a of simple complete denervation of biceps brachii served as control.
切断大鼠右侧胫神经形成失神经腓肠肌实验模型。
The animal model of nerve injury and gastrocnemius denervation was established by cutting the right tibial nerve.
方法：应用神经兴奋性测试仪测试失神经支配程度。
Methods: Denervation degree was measured with nerve excitability measurement apparatus.
失神经骨骼肌纤维变细，排列紊乱，并有凋亡小体出现。
Fiber thinning and disorderly arrangement of denerved skeletal muscles were observed and apoptotic bodies were detected.
结果失神经后2周，游离神经末梢和感觉小体开始溃变；
Results The degeneration changes of free nerve endings and sensory corpuscles were observed after 2 weeks.
目的探讨失神经支配骨骼肌超微结构及酶组织化学变化。
Purpose to study the change of ultrastructure and enzyme histochemistry of denervated skeletal muscle.
目的研究神经肌蒂移植对骨骼肌失神经肌萎缩的预防作用。
Objective To investigate the effect of neuromuscular pedicle transplantation in preventing the atrophy in denervated muscle.
结果肌细胞直径及截面积随失神经支配时间延长呈进行性下降；
Results The myocyte diameter and cross section were reduced progressively along with the duration of muscle denervation.
失神经后第5、6个月及1年以后为纤颤电位波幅的显著下降期；
The fibrillation potential amplitude decreased significantly at the 5th, 6th month and the time over 1 year( P< 0.05).
大量的国内外研究证实失神经支配后骨骼肌肌纤维与细胞凋亡相关。
Studies of domestic and aboard confirmed that denervation skeletal muscle fiber is related to cell apoptosis.
干预：将实验组大鼠双侧下肢坐骨神经切断，制成肌肉失神经支配模型。
INTERVENTION: the model of the denervated gastrocnemius and soleus was made by clipping the sciatic nerve.
目的：探讨不同程度失神经支配后，眼轮匝肌和口轮匝肌的形态学变化。
Objective: To explore the morphological changes in orbicularis oculi muscle and orbicularis oris muscle after denervation.
我们研究通使用强烈的电刺激对长期失神经支配的股四头肌的恢复潜力。
We investigated the restorative potential of intensive electrical stimulation in a patient with long-standing quadriceps denervation.
结论：舌下神经颏舌肌蒂植入能使失神经胸大肌瓣重新获得良好的神经再支配。
Conclusion:The denervated pectoralis major myoflap can be reinnervated by hypoglossal-genioglossus muscle neuromuscular pedicle transplantation.
结论：失神经支配程度是FP康复诊断的指标，并与髓鞘和轴突破坏程度有关。
CONCLUSION: the degree of denervation is a marker for rehabilitative diagnosis of FP, and is related to the destruction degree of myelin sheath and axon.
目的：设计及建立选择性失神经咬肌的动物模型，为临床外科提供实验资料和理论依据。
AIM: to design and establish the animal model of selectively denervated masseter, in order to provide experimental data and theoretical evidence for clinical surgery.
目的研究人体骨骼肌失神经后肌细胞生成素的表达变化，了解失神经骨骼肌的再生状态。
Objective To detect the change of expression of myogenin in human skeletal muscle after denervation and understand the regeneration of denervated skeletal muscle.
骨骼肌卫星细胞在失神经支配后增多，但不能分化为成熟肌纤维，以致最后减少甚至耗竭。
Muscle satellite cells increased after denervation, but then they decreased and disappeared because they could not differentiate to mature muscle fibers.
失神经支配肌肉的神经营养活性是各种营养因子的共同作用结果，不能用单一某种神经营养因子来代表。
Yet, the neurotrophic activity of the denervated muscle results from not only NGF, but also the integration of multiple neurotrophic factors.
结论：兔耳大神经端侧吻合植入失神经皮瓣后，供神经的轴突能长入神经移植体，并最终形成具有功能的感觉未梢。
Conclusion:The axonal reinnervation of sensory nerve endings from the proximal stump to distal implanted nerve in end-to-side nerve neurorrhaphy is feasible.
采用健康成年鸡的自身对照实验，研究鸡的前背阔肌（ALD）和后背阔肌（PLD）失神经后胰岛素受体的改变。
The changes in insulin receptors were studied in chick anterior latissimus doris (ALD) and posterior latissimus doris (PLD) 4 weeks after denervation.
结论：HGF可以促进正常肌肉与失神经肌肉之间运动神经末梢的再生，加速再生的神经末梢与失神经肌肉建立新的终板联系。
CONCLUSION: HGF can promote the regeneration of motor nerve axons and accelerate the establishment of new motor endplates in the denervated muscles.
本文通过应用副神经。胸锁乳突肌蒂瓣植入环杓后肌的动物实验，使失神经支配的环杓后肌重新获得功能，探索治疗喉返神经麻痹的新方法。
In order to find a new method to treat paralyzed vocal cord, accessory sternocleidomastoid neuromuscular pedicle flap embeded in denervated posterior cricoarytenoid muscle was studied in dogs.
本文通过应用副神经。胸锁乳突肌蒂瓣植入环杓后肌的动物实验，使失神经支配的环杓后肌重新获得功能，探索治疗喉返神经麻痹的新方法。
In order to find a new method to treat paralyzed vocal cord, accessory sternocleidomastoid neuromuscular pedicle flap embeded in denervated posterior cricoarytenoid muscle was studied in dogs.
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