本文就其结构与功能、基因表达的调控以及应用前景作一综述。
Its structure, function and regulation of gene expression and application prospect are introduced comprehensively here.
关于神经特异性基因表达的调控的分子机理一直受到人们的关注。
The mechanism of neural-specific gene expression is of considerable general interest to scientists.
丁酸的作用机制是多方面的,其中许多机制与其参与基因表达的调控作用有关。
The mechanism of butyric acid is multifaceted and its involvement in the regulation of gene expression.
许多植物基因表达的调控发生在转录水平上,主要受顺式元件和反式因子的调控。
In plants, the expression of many genes is regulated at transcriptional level, and mostly by cis - and trans-acting elements.
真核生物基因表达的调控是目前分子生物学研究中重要的前沿领域,形成了多个热点。
Research on gene expression regulation in Eukaryota is one of the leading molecular research fields. There are several research hot focuses in this field.
要研究RNA对基因表达的调控就必须对RNA -蛋白质之间相互作用的方式进行研究。
Research of RNA-protein interaction is important for the study of RNA regulation in gene expression. The.
HDAC活性在基因表达的调控中发挥关键作用,HDAC是一种经过临床验证的癌症靶标。
HDAC activity plays a key role in the regulation of gene expression, and HDAC is a clinically validated cancer target.
肿瘤最基本的生物学特征之一是细胞呈无限失控生长,其过程涉及基因质的变化和基因表达的调控异常。
The unlimited proliferation is one of the most fundamental biologic behavior of all tumors, Which is involved in abnormalities of multiple gene alterations and regulations.
反义rna广泛存在于各类生物中,它作用于DNA的复制、转录、转译的过程,实现对基因表达的调控。
Antisense RNA exists in all kinds of living beings wildly. It ACTS on the course of the replication of DNA, transcription and translation, which realize the regulation and control of gene expression.
基因表达的调控是通过基因调控系统实现的,而该系统的结构又由DNA、RNA、蛋白质及小分子之间的关系网络决定。
The regulation of gene expression is achieved through genetic regulatory systems, which are structured by networks of interactions between DNA, RNA, proteins, and small molecules.
RNA干涉现象以一种非常明确的方式抑制了基因表达,对于基因表达的调控、病毒感染的防护、控制跳跃基因具有重要的意义。
RNA interference is a very important mechanism for the regulation of gene expression, participates in defense against viral infections, and keeps jumping genes under control.
主要讨论了UV -B信号途径及光受体,UV - B诱导的DNA损伤、转座子激活,UV - B对光合器官的分子伤害及相关基因表达的调控等。
UV B signaling pathway and specific UV B receptor, DNA damage, activation of transposons, molecular damage of photosynthetic apparatus and UV B regulation of related gene expression were included.
过去的大约40年里,科学家已经知道了基因是如何运作的,他们知道了基因的结构,他们如何复制,如何调控和表达,以及最重要——如何操纵他们。
FOR around 40 years scientists have understood how genes work. They have known the structure of genes, how they replicate, how they are controlled and expressed and, crucially, how to manipulate them.
之所以这样说是因为这些基因编码的并不是能够在人类细胞中表达并且调控某些生物过程的蛋白质。
This is because they code for something other than the proteins that are expressed in human cells and that regulate biological processes.
因此,大体上可以这么形容,在墙上的东西就是开关DNA,手指是调控器,基因表达就是打开灯或关闭灯。
So, very crudely, the thing on the wall is the switch DNA, your finger is the regulator, and gene expression is the light turning on or turning off.
当调控分子与这个开关dna结合时,相邻的基因便开始表达或终止表达。
When regulatory molecules bind to this switch DNA, the contiguous gene is either expressed or prevented from being expressed.
这项工作还未结束,但我们认为,大脑中的基因表达及调控——至少是研究个体老化的一个指针。
"It's a work in progress, but we believe that the expression of genes in the brain and how they are regulated is at least an indicator of how well someone is aging," Yankner says.
组蛋白是染色质的核心,其尾部共价修饰在基因表达调控中有重要作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
有的情况下,细胞不管怎样还是维持正确的量;别的情况下,CNVs对调控另外的基因表达的DNA区域有影响,使问题更加复杂。
Sometimes cells make the correct amount anyway; other times CNVs affect DNA regions that regulate the expression of still other genes, making the problem more complicated.
每个基因含有启动控制区,以调控基因的表达。
Each gene includes starts the control area, regulates the gene the expression.
差异表达的基因的功能涉及细胞生长增殖调控、凋亡、细胞周期、应激反应、转运及代谢酶等方面。
The expressions of the various genes modulated cell growth and proliferation, apoptosis, cell cycle, stress response, transporters, chaperones, transcription regulation and drug metabolism.
基因转录是遗传信息传递和表达的枢纽,是基因表达调控机制发挥作用的重要环节。
Transcription is the first major step in gene expression, and constitutes an important point of genetic information flow.
新发现的位置核苷酸,叫做强甲基胞嘧啶,位于动物细胞内,提示着有新的基因表达调控机制。
The discovery of a previously unknown nucleotide, called hydroxymethylcytosine, inside animal cells suggests a new mechanism for regulating gene expression.
猴hcbp6同源基因的克隆化为研究不同种属来源的HCBP6基因的结构域功能、表达与调控等研究奠定了基础。
The successful cloning of monkey HCBP6 gene paves a way for the study of the relationship of structure and function of HCBP6 genes from different species.
研究发现发育脑中的甲状腺激素通过调控特异基因的表达来发挥作用。
It reveals that thyroid hormone plays roles by regulating the expression of specific gene.
探讨这些基因逃避X失活的机制有助于理解X染色体失活是如何对基因表达进行调控的。
Study on the mechanisms of 'escape' is helpful to the understanding of gene regulation by X inactivation.
基因表达受不同层次的调控。
本文综述了生物素的营养生理作用及其对基因表达调控的影响。
The nutritional and physiological function of biotin and its effects on gene expression were reviewed in this paper.
本文回顾了近年来营养素对基因表达调控作用的研究进展。
The research progresses in regulation of gene expression by nutrients in recent years are reviewed.
本文回顾了近年来营养素对基因表达调控作用的研究进展。
The research progresses in regulation of gene expression by nutrients in recent years are reviewed.
应用推荐