目的：观察嗅鞘细胞对胚胎脊髓后角神经元突起生长的影响。
Objective:To investigate effects of olfactory ensheathing cells(OECs)on neurite outgrouth of embryonic spinal cord dorsal horn neurons in vivo.
结论嗅鞘细胞与大鼠尾状核神经元共培养可促进神经元生长。
Conclusions: OECs promote the growth of the co-cultured rat caudate nucleus neurons.
结论嗅鞘细胞移植有助于脊髓损伤患者脊髓神经功能的恢复。
Conclusion OECs transplantation can help patients with complete spinal cord injury to recover their spinal cord function obviously.
结论脂肪干细胞在嗅鞘细胞生长微环境中能向嗅鞘样细胞分化。
Conclusion OECs and hydrogel promote differentiation of adipose-derived stem cells into OEC-like cells.
目的：观察嗅鞘细胞和骨髓间充质干细胞联合移植修复脊髓损伤的效果。
OBJECTIVE: To investigate effects of OEC and BMSC transplantation for treating injured spine cord.
取12周左右的流产新鲜人胚胎(产妇知情同意)用于嗅鞘细胞的培养纯化。
Fresh 12-week aborted human embryo was used for culture and purification of human OECs (Informed consent was obtained from the parturient).
目的探讨神经干细胞与嗅鞘细胞联合移植对大鼠创伤性脑外伤的治疗作用。
Objective To study the effect of neural stem cells and olfactory ensheathing cells transplantation on traumatic brain injury in rats.
嗅鞘细胞在移植治疗轴突损伤和去髓鞘化疾病的研究中显示出潜在的临床应用前景。
OEC transplantation has emerged as a promising experimental therapy of axonal injuries and demyelinating diseases.
因此，我们所能看到的远景是单独的应用嗅鞘细胞移植所获得的临床受益是有限度的。
We conclude that for the foreseeable future the clinical benefits of OEC transplants alone are likely to be modest.
结果嗅鞘细胞移植后3个月、6个月和1年随访，6例患者的脊髓功能均有不同程度的改善。
All of 6 patients expressed complete spinal cord injury. Results Between 3 months and 1 year after OECs transplantation the patients showed recovery in spinal cord function.
模型对照组呈阴性表达。结果进一步验证了嗅鞘细胞移植治疗大鼠缺血性脑损伤是可行有效的。
Negative expression was detected in the model control group. Results show that the olfactory ensheathing cell transplantation is effective on ischemic brain injury in the rats.
结论：在周围神经损伤后脊髓及神经节内神经元有凋亡发生，嗅鞘细胞移植对神经元凋亡有保护作用。
CONCLUSION: There are apoptotic neuron in the spinal cord and ganglion after peripheral nerve injury, while the OECs has protective effect on apoptotic neurons.
据我们目前所知，我们所鉴定的嗅鞘细胞分泌蛋白质表达谱的蛋白质数据是目前国际上最大的一个溴鞘细胞蛋白质数据库。
As far as we know, our olfactory ensheathing cells secreted protein expression profile data is now the largest international database of olfactory ensheathing cells secreted protein.
据我们目前所知，我们所鉴定的嗅鞘细胞分泌蛋白质表达谱的蛋白质数据是目前国际上最大的一个溴鞘细胞蛋白质数据库。
As far as we know, our olfactory ensheathing cells secreted protein expression profile data is now the largest international database of olfactory ensheathing cells secreted protein.
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