目的探讨吉西他滨在乳腺癌化疗中的作用。
Objective To study the antitumor effect of gemcitabine in chemotherapy with breast cancer.
吉西他滨目前是作为胰腺癌术后的标准治疗药物。
Gemzar treatment is now considered the standard of care for pancreatic cancer following surgery.
结果:合成了盐酸吉西他滨,总收率15.8%。
目的:合成抗癌药物盐酸吉西他滨并改进合成工艺。
Objective: To synthesize of gemcitabine hydrochloride and optimize the process.
吉西他滨是近年来治疗晚期非小细胞肺癌的有效新药。
Gemcitabine is a new active drug in the treatment of advanced non small cell lung cancer (NSCLC).
吉西他滨和卡培他滨的组合有时用来治疗转移性肾细胞癌。
A combination of gemcitabine and capecitabine is sometimes used to treat metastatic renal cell cancer.
吉西他滨30分钟静脉滴注是晚期胰腺癌的标准治疗方案。
Gemcitabine (iv over 30 minutes) is the standard therapy for inoperable pancreatic cancer of advanced stage.
同时,这些患者既往不能有包含吉西他滨或者顺铂的化疗史。
Patients could not have had prior chemotherapy with gemcitabine or cisplatin.
采用吉西他滨和CD 40抗体治疗后,30%的小鼠肿瘤瘤体缩小。
After treatment with gemcitabine and CD40 antibody, the tumors shrank in 30% of the animals.
厄罗替尼布联合卡培他滨同样用于一线药物吉西他滨治疗失败的患者。
Erlotinib is also being evaluated in combination with capecitabine in patients who failed first-line therapy with gemcitabine.
目的观察吉西他滨联合伯尔定治疗晚期非小细胞肺癌的疗效及毒副作用。
Objective to observe the efficacy and toxicity of gemcitabine plus Carboplatin in the treatment of advanced non-small-cell lung cancer (NSCLC).
目的:探讨术后后装放疗加吉西他滨全身化疗对原发性肝癌的治疗效果。
Purpose: To evaluate the effect of postoperative after-loading radiotherapy with the use of gemcitabine in 22 patients with primary liver cancer.
目的探讨放射性125I粒子植入联合吉西他滨治疗进展期胰腺癌的临床价值。
To explore the significance of implanted 125i radioactive particles into tumor combined with gemcitabine to treat extended local pancreas cancer.
目的观察吉西他滨联合卡培他滨治疗蒽环类耐药性晚期乳腺癌的疗效与毒性反应。
Objective To observe the results of gemcitabine combined with capecitabine on anthracycline-resistant breast cancer.
结论:吉西他滨联合顺铂的新辅助化疗耐受性好,并且没有破坏胰腺癌的可手术性。
Conclusion: Neoadjuvant chemotherapy with gemcitabine and cisplatin is well tolerated and does not impair resectability of pancreatic cancer.
吉西他滨合用贝伐单抗的患者中位生存期为5.7个月,而单用吉西他滨者为6个月。
The median survival for patients taking both Avastin and Gemzar was 5.7 months compared with 6.0 months for patients taking Gemzar alone.
对复发性乳腺癌患者,吉西他滨的疗效则明显优于蒽环类和紫杉类药物(P<0。01)。
Results In primary breast cancer, the antitumor effect of taxane is better than anthracycline and gemcitabine(P <0.01).
目的观察不同剂量、用法的吉西他滨联合伯尔定治疗晚期非小细胞肺癌的疗效和不良反应。
Objective to observe the efficacy and toxicity of gemcitabine of different dosages and methods plus carboplatin in patients with advanced non-small-cell lung cancer (NSCLC).
目的观察吉西他滨联合厄洛替尼方案治疗进展期胰腺癌的疗效、临床获益反应和毒性反应。
ObjectiveTo evaluate the efficacy, clinical benefits and toxicities of gemcitabine combined with erlotinib for advanced pancreatic cancer.
该研究中,302名患者接受吉西他滨合用贝伐单抗,300名患者接受吉西他滨和安慰剂。
The study researchers assigned 302 patients to receive Avastin and Gemzar and assigned an additional 300 patients to receive Gemzar plus placebo.
目的观察了解吉西他滨单药治疗老年晚期非小细胞肺癌(NSCLC)的临床疗效和毒性反应。
Objective: to evaluate the clinical effect and toxicity of gemcitabine monotherapy in the treatment of elder advanced non-small cell lung cancer (NSCLC).
这些满足适应症的患者被随机分至单用吉西他滨组(204例)和顺铂-吉西他滨联用组(206例)。
Eligible patients were randomized to either treatment with gemcitabine alone (204 participants) or in combination with cisplatin (206).
目的:评价国产药与进口药盐酸吉西他滨治疗非小细胞肺癌(NSCLC)的疗效、安全性及不良反应。
Objective: To evaluate the curative effect, safety and adverse reaction of domestic and imported gemcitabine hydrochloride in non-small cell lung cancer (NSCLC).
接受氟尿嘧啶联合亚叶酸方案治疗或是吉西他滨方案治疗患者的中位生存期分别为23.0个月及23.6个月。
Median survival for patients treated with fluorouracil plus folinic acid was 23.0 months and for patients treated with gemcitabine was 23.6 months.
第二种方法是针对肿瘤的靶向治疗,可以应用新的药物吉西他滨联合铂作为化学治疗,我想这个有可能会成为标准治疗。
The second approach is therapeutically targeting the cancer. One can use the new regiment of gemcitabine plus platinum as chemotherapy which I think will likely be the standard of care.
吉西他滨-厄洛替尼联合贝伐单抗治疗有很好的耐受性:得到的安全数据和先前描述的个性化药物治疗得到的安全数据不同。
Treatment with bevacizumab plus gemcitabine-erlotinib was well tolerated: safety data did not differ from previously described safety profiles for individual drugs.
该工业化生产盐酸吉西他滨的合 成工艺总收率为17.9%,纯度在99.8%以上,特别适用于工业化生产盐酸 吉西他滨。
The total yield of the synthesis process is 17.9 percent and the purity is above 99.8 percent, thus being particularly applicable to the industrial production of gemcitabine hydrochloride.
目的评价长春瑞滨(NVB)与顺铂(DDP)及吉西他滨(GEM)与顺铂联合化疗治疗晚期非小细胞癌(NSCLC)的疗效及毒副作用。
Objective To evaluate the toxicity and clinical activity of navelbine(NVB) plus cisplation(DDP) and gemcitabine(GEM) plus cisplation in the treatment of advanced non-small cell lung cancer(NSCLC).
由英国癌症研究所基金资助,这项研究将检验名为GV 1001的疫苗和两种化疗药物吉西他滨和截瘤达对局部晚期和远处转移的胰腺癌的作用。
Funded by cancer Research UK, the trial will test the vaccine GV1001 alongside two chemotherapy drugs gemcitabine and capecitabine on patients with locally advanced and metastatic pancreatic cancer.
由英国癌症研究所基金资助,这项研究将检验名为GV 1001的疫苗和两种化疗药物吉西他滨和截瘤达对局部晚期和远处转移的胰腺癌的作用。
Funded by cancer Research UK, the trial will test the vaccine GV1001 alongside two chemotherapy drugs gemcitabine and capecitabine on patients with locally advanced and metastatic pancreatic cancer.
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