本发明提供了该抗体的可变区序列。
The invention provides the variable region sequence of the antibody.
方法整合子PCR法扩增整合子的可变区;
Methods The variable region of integron was amplified by integron PCR.
结果表明,与小鼠免疫球蛋白可变区同源性极高。
The results showed it had high autoploidy with mouse Ig variable fragment.
报道一种克隆免疫脾细胞中抗体可变区基因的新方法。
A novel method in cloning antibody variable genes from immunized spleen cells was described in the report.
推导的氨基酸序列具有典型的抗体轻、重链可变区特征。
Two amino acid sequences deduced had typical features of Ig heavy and light chains' variable regions.
结果序列测定初步确定所克隆的是功能性抗体可变区基因。
Results The cloned antibody variable regions genes were approved functional by sequencing.
目的:获得抗人视网膜母细胞瘤单克隆抗体轻链可变区基因。
Objective: to acquire the variable region gene of light chain of monoclonal antibody against human retinoblastoma.
本发明公开了具有改变的可变区的抗cd 19B4抗体。
Anti-CD19 B4 antibodies with modified variable regions are disclosed.
结果:克隆的基因序列符合小鼠轻、重链可变区基因的特征;
RESULTS: The VH and VL genes were homologous with the published gene sequences of mouse antibody variable region.
核苷酸序列分析表明所克隆基因分别为抗体轻、重链可变区基因。
The nucleotide sequence analyses indicated that the cloned genes coded the variable light and heavy chain domains from mouse antibodies respectively.
方法利用RTPCR 方法扩增抗体可变区基因并表达于噬菌体表面。
Methods The genes encoding antibody variable regions were cloned by RT PCR from hybridoma cells and expressed on bacterial phage surface.
轻链可变区和恒定区均包含保守的半胱氨酸,形成链内和链间二硫键。
The cysteine residues involved in the formation of disulfide bonds are completely conserved among fish IgL.
而要研制基因工程抗体,鼠源性抗体可变区基因的克隆与测序是关键。
To generate the recombinant antibodies, the key point is the cloning and the sequencing of the VH and VL genes from antibody secreting hybridoma cell line.
目的获取系列鼠抗人CD分子单抗的轻链及重链可变区基因并进行克隆和测序。
Objective to obtain the VH and VL variable region genes of murine McAbs to human CD molecule.
变域变分原理,可以结合可变区为功能,这使得它可以同时计算流场的变量域。
Variable-domain variational principles can couple the variable domain into functional, which makes it possible to calculate the flow field with the variable-domain simultaneously.
应用放射免疫竞争抑制试验测定抗体的配位特异性,并对抗体的可变区序列进行比较。
METHODS The paratope mapping of antibodies was determined by competitive inhibition in radioimmunoassay and the sequences of variable regions among the antibodies were compared.
方法利用RT -PCR方法从杂交瘤细胞株2f 3中扩增出单克隆抗体重链可变区和轻链可变区基因。
Methods the genes were amplified from the heavy (VH) and light (VL) chain variable regions of hybridoma cell strain 2f3 by RT-PCR and identified by DNA sequencing.
对V6和V3可变区的焦磷酸测序,确定了3300- 5700个分类,这些分类总体上解释了超过99%的由这些样本获得的可变区的序列标签。
Pyrosequencing of the V6 and V3 variable regions identified 3,300-5,700 taxa that collectively accounted for over 99% of the variable region sequence tags that could be obtained from these samples.
比如,森林里就有大量的相邻小气候区,其环境截然不同,这是因为刚刚我所提到的各种不同的可变因素。
In the forest, for example, there can be a number of very different microclimates close to each other, because of all the variables I just mentioned.
特定工作区或流中的某个组件的不可变副本称为基准。
An immutable copy of a component in a particular workspace or stream is called a baseline.
本地变量空间用作该函数的通用存储空间,寄存器保存区用于保存函数所使用的非可变寄存器的值。
The local variable space is used as a general storage area for the function, and the register save area is used to save the values of non-volatile registers that the function USES.
首先爱尔兰和西班牙的房价是整个欧元区高估最严重的;其次,雪上加霜的是,大部分按揭贷款都以可变利率维系,而其他地区,按揭利率大多都是固定不变的。
In Ireland and Spain home prices are the most overvalued in the zone; worse, the bulk of mortgages are at variable rates. Elsewhere, most mortgage rates are fixed.
在本研究区中,采用了SN388地震仪、中密炸药激发、检波器组合并深埋检波器以及可变的观测系统参数,改进了施工方法。
We used SN388 seismic instrument, grouping and deep embedment geophone, variable parameter of viewing system in this researching area, thus improved construction ways.
可根据实验模型的布局特征选择在水平面内可变形状的零洞壁干扰目标线,以改善模型区残余干扰分布特性。
The transformable target line without wall interference can be chosen according to the test model to improve the residual interference distribution in model area.
现代网络设备常采用固定长度缓冲区机制来缓冲可变长度数据包,或采用信元机制将可变长度数据包进行定长化处理后再完成缓冲操作。
For processing variable length packet, current routers usually separate the packet into the smaller fixed-size one before buffering, or simply provide the packet with a fixed-length buffer.
要解决该问题,可采用大小可变的滑动窗来搜索局部的最大同质区,最大同质区的大小能自适应局部纹理的变化。
Aiming at this problem, a flexible-size sliding-window is used to search the maximum-size homogenous area, and consequently the size of homogenous area can be adaptive to the local texture.
根据夹断电压能确定可变电阻区与饱和区的分界点,使场效应管可靠地工作在饱和区的原理。
On the grounds of the pinch-off voltage, the cut-off point of variable resistance area and saturation area can be fixed, so the field effect tube can reliably work in the saturation area.
根据夹断电压能确定可变电阻区与饱和区的分界点,使场效应管可靠地工作在饱和区的原理。
On the grounds of the pinch-off voltage, the cut-off point of variable resistance area and saturation area can be fixed, so the field effect tube can reliably work in the saturation area.
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