叠氮胸苷(azt)整合入线粒体dna是另一种可能。
现在要说出叠氮胸苷(azt)在线粒体的毒副作用的机制还太早。
It is too early to say what the mechanism of mitochondrial toxicity of AZT is.
叠氮胸苷(azt)缺少可以使DNA继续复制的特殊化学基团(羟基),这就导致了DNA合成的过早终止。
However, modified AZT molecules lack a specific chemical group (a hydroxyl group) that would allow DNA replication to continue. This results in premature termination of DNA synthesis.
叠氮胸苷(AZT)这类药可以影响细胞的能量工厂-线粒体中DNA的复制,对进行高效抗逆转录病毒治疗法(HAART)的患者有潜在的致命副作用。
Drugs like AZT may interfere with DNA replication in the mitochondria, the energy factories of our cells, and can lead to potentially fatal side effects in patients undergoing HAART treatment.
叠氮胸苷(AZT)这类药可以影响细胞的能量工厂-线粒体中DNA的复制,对进行高效抗逆转录病毒治疗法(HAART)的患者有潜在的致命副作用。
Drugs like AZT may interfere with DNA replication in the mitochondria, the energy factories of our cells, and can lead to potentially fatal side effects in patients undergoing HAART treatment.
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