结论双氯芬酸二乙胺盐凝胶经皮给药安全。
Conclusion Diclofenac diethylamine salt gel is safe for transdermal administration.
目的观察双氯芬酸二乙胺盐凝胶经皮用药的安全性。
Objective To observe the safety of diclofenac diethylamine salt gel after external use.
目的：制备双氯芬酸二乙胺凝胶并考察其释药影响因素。
Objective:To prepare diclofenac diethylammonium gel and study the factors affecting drug release by transdermal test in vitro.
方法：采用正交试验，对双氯芬酸二乙胺凝胶进行体外透皮试验，以透皮扩散速率常数为考察指标。
Method: Orthogonal design was used in transdermal test with transdermal diffusion rate constant as selection standard.
方法：采用正交试验，对双氯芬酸二乙胺凝胶进行体外透皮试验，以透皮扩散速率常数为考察指标。
Method: Orthogonal design was used in transdermal test with transdermal diffusion rate constant as selection standard.
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