• 问题关键在于找到正确的诱导干细胞分化成心脏细胞,神经细胞,制造胰岛素的细胞或者其他细胞的生长因子的正确方法。

    The key lay in finding just the right recipe of growth factors and nutrients to induce a stem cell to become a heart cell, a neuron, an insulin-making cell or something else.

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  • 在实验中,科学家们已经成功地诱导胚胎干细胞分化为心肌细胞和分泌胰岛素的胰腺细胞。

    In the laboratory, scientists have been able to induce embryonic stem cells to develop into heart muscle cells or insulin-producing cells of the pancreas.

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  • 目的:观察1,25 -二羟基维生素d3对白血病细胞株hl - 60的分化诱导作用及其分子机制。

    AIM To investigate the differentiation induction of 1 25-dihydroxyvitamin D3 on leukemic cell line HL-60 and its molecular mechanism.

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  • 方法:改进显示缺氧心肌的碱性复红法,即延长苏木素染色时间并增加盐酸酒精分化的步骤。

    Methods: the basic fuchsin method used to show the anoxic cardiac muscle was modified by prolonging the hematoxylin staining time and adding a step of hydrochloric acid alcohol differentiation.

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  • 单细胞反转录酶聚合链式反应检测胰岛素促进因子基因实验中,选择12个单个胰腺干细胞进行检测,另取12个单个未分化的干细胞作为对照。

    In the detection of IPF1 gene with single cell RT-PCR, 12 single pancreatic stem cells were detected, and another 12 undifferentiated single pancreatic stem cells were taken as controls.

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  • 目的:本文就近年来干细胞诱导分化为胰岛素分泌细胞的研究进展做一综述。

    OBJECTIVE: This article is a review about the research progress of the differentiation from stem cells into islet-producing cells.

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  • 纳入标准:干细胞向胰岛素分泌细胞诱导分化的研究进展。

    Inclusive criterion: Articles about research progress of the differentiation from stem cells into islet-producing cells were selected.

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  • 胰岛素样生长因子系统在调节细胞增殖、分化与抑制凋亡中发挥重要作用。

    Insulin-like growth factor (IGF) system plays an important role in regulating cell proliferation and differentiation, and inhibiting apoptosis.

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  • E 钙粘素表达与肿瘤细胞分化呈正相关;

    The expression of E-cadherin was associated with differentiation.

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  • 目的:探讨染料木素体外对大鼠成骨细胞增殖与分化的影响。

    Objective: To study the effects of genistein on proliferation and differentiation of cultured osteoblasts in vitro.

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  • 对于愈伤组织的再分化,不仅需要细胞分裂素,而且诱导培养基中生长素浓度的影响也是显著的。

    With regard to the callus redifferentiation, not only kinetin is needed, but also the effect of auxin concentration of the induction medium is also remarkable.

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  • 本研究结果提示,上述凝集素在人胚食管上皮的结合部位的分布情况及染色强度,可作为该上皮细胞的发育、分化程度的标志之一。

    It is suggested that the distribution of lectin binding and staining intensity might serve as a marker of development and differentiation of esophageal epithelium.

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  • 月光花素在十几种农作物上均有很强的生理活性;特别是对植物愈伤组织的生长和分化有显著的调节作用。

    It has distinct effects on physiological activities in more than ten kinds of crops, especially for the growth and differentiation of plant callus.

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  • 结果:二甲胺四环素在体外具有刺激骨髓基质细胞和成骨细胞增殖的作用,但抑制细胞的分化。

    Result: minocycline can stimulate the proliferation of osteoblast and marrow stromal cell, but also can restrain the differentiation.

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  • 外源生长素和细胞分裂素是诱导离体培养细胞分化与增殖所必需的,2,4-D是诱导胚性愈伤组织的重要激素。

    The exogenous auxin and cytokinin are necessary to induced differentiation and proliferation of cells of culture in vitro. 2,4-D is an important hormone of induced embryogenic calluses.

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  • 目的探讨TPO(血小板生成素)基因导入对t细胞增殖和分化影响的规律。

    To elucidate the regular effect pattern of thrombopoietin (TPO) on the differentiation and proliferation of t lymphocytes via gene transference.

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  • 目的探讨SW872前脂肪细胞分化过程中脂联素受体基因表达的变化。

    Objective to explore genes expression of adiponectin receptors during differentiation of SW872 preadipocytes.

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  • 结论辣椒素对银屑病小鼠模型的作用可能与促进表皮细胞正常分化和抑制表皮细胞增殖有关。

    Conclusion the effect of Capsaicin on psoriasis animal model may be related to promoting the formation of granular cells and inhibiting the proliferation of epidermic cells.

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  • 骨生成素是一类蛋白质生长因子,在动物(包括人类)的生长发育过程中对组织器官的决定与分化起重要作用。

    Bone morphogenetic proteins (BMPs) are growth factors that involved in the growth, differentiation and repair of a wide variety of tissues.

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  • 探讨小鼠骨髓干细胞有无被诱导分化为胰岛素分泌细胞的可能性。

    ObjectiveTo study whether the mouse bone marrow-derived stem cells have the possibility to be induced into insulin-secreting cells.

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  • 结论:在3t3- L1脂肪前体细胞分化过程中脂联素基因表达逐渐上调,可能有利于脂肪细胞的分化成熟。

    Conclusions: Adiponectin gene mRNA expression is up-regulated during 3t3-l1 preadipocyte differentiation. It may contribute to the adipocyte differentiation and obesity.

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  • 目的探讨白细胞介素10对肾小管上皮细胞转分化的影响,并初步讨论其作用机制。

    Objective To investigate the effect of interleukin-10(IL-10) on epithelial to mesenchymal transition in human renal tubular cells and relevant mechanisms.

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  • 目的:研究骨髓源性神经干细胞在体外培养及诱导分化条件下能否分泌去甲肾上腺素(NE)。

    Objective: To study whether the neural stem cells derived from bone marrow stromal cells (BMSCs) could excrete neural biological activity material-noradrenaline (ne) in vitro.

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  • 目的以正丁酸钠为平行对照,比较观察鲎素和癌细胞诱导分化物对人胃癌细胞形态与超微结构变化的影响。

    Objective To compare the morphology and ultrastructure changes of human gastric adenocarcinoma cell line treated by tachyplesin and n-sodium butyrate.

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  • 目的研究可水解单宁诃子酸和特里马素I对氯化高铁血红素和丁酸钠诱导K562细胞红系分化的影响。

    Objective Effects of plant tannins, chebulinic acid and tellimagrandin I on chemically induced hemoglobin synthesis in K562 cells were investigated.

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  • 本文对丁酸钠诱导分化的人白血病细胞株k- 562细胞的胰岛素受体酪氨酸蛋白激酶性及细胞内源性底物进行了研究。

    In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.

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  • 结论淫羊藿甙不仅能促进成骨细胞的分化,还能增强其增殖能力,而葛根素主要是通过刺激分化来增强成骨细胞的活力。

    Conclusion Icariine has the effect of increasing the proliferation and differentiation of osteoblasts while Puerarin mainly stimulates the differentiation of osteoblasts.

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  • 结论激活素a能促进肾小管上皮细胞增殖、转分化,提示激活素a可能在肾小管间质纤维化中起重要作用。

    Conclusions activin a can promote the proliferation and transdifferentiation of renal tubule cells, which suggests that activin a may play an important role in interstitial fibrosis of renal tubule.

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  • 结论激活素a能促进肾小管上皮细胞增殖、转分化,提示激活素a可能在肾小管间质纤维化中起重要作用。

    Conclusions activin a can promote the proliferation and transdifferentiation of renal tubule cells, which suggests that activin a may play an important role in interstitial fibrosis of renal tubule.

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