依托泊苷能稳定酶催化性循环中的一种共价的拓扑异构酶ii裂解的DNA中间复合物，导致基因组不稳定性和细胞死亡(2,3)。
Etoposide stabilizes a covalent topoisomerase II-cleaved DNA intermediate complex in the catalytic cycle of the enzyme, leading to genomic instability and cell death (2, 3).
我想象它们的样子，通过共价键结合的分子链。
I'm imagining something like, covalently bonded chains that have links between them.
当我们刚开始介绍共价键的时候，我们说过电子是被共用的，但是共用却不一定是均等的。
So as we said when we first introduced covalent bonds, it's a sharing of electrons, but it's not always an equal sharing.
共价催化涉及底物与活性位点中的残基或与辅因子形成瞬时共价键。
Covalent catalysis involves the substrate forming a transient covalent bond with residues in the active site or with a cofactor.
配位共价键是其中两个键合电子均来自该键所涉及的原子之一的键。
A coordinate covalent bond is one where both bonding electrons are from one of the atoms involved in the bond.
DNA甲基化是脊椎动物DNA唯一的自然共价修饰方式。
DNA methylation is the unique natural covalent modification of vertebrate animals.
量子点与生物大分子的连接方式主要有共价耦联结合和静电吸附作用两种。
The two main methods of the connection between QDs and biological molecules are covalent coupling and electrostatic adsorption.
在组蛋白上发生的共价修饰组合，具有功能意义，能被蛋白质识别。
Combinations of covalent modifications on histones that have a functional significance and are recognized by proteins.
超分子化学是小的分子单元通过非共价键自组装成大的超级分子的化学。
The super molecule chemistry is that small molecule units have assembled big molecule with non-covalent bond by themselves.
化学的直观告诉我们离子项对波函数的贡献比共价项小得多。
Chemical intuition tells us that ionic terms should make substantially less contribution to the wave function than covalent terms.
树脂固化时收缩应力的主要原因是单体之间的分子间距离缩短变为共价距离。
The main reason of shrinkage stress during curing period is the change from distance between monomer molecules to covalent distance .
共价键的定义是什么？
然后鲍林更进一步，说这是一个完全的共价成分。
And so Pauling went further and said this is the purely covalent component.
而关于共价键最关键的一点就在于共用的概念。
And the key word for covalent bonds is the idea of being Shared.
他有许多著名的发现，其中一个便是共价键。
He's famous for a lot of things, one of which is covalent bonding.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰，在基因的表观遗传转录调控中起着关键的作用。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
有研究显示，在碳化二亚胺的存在下，蛋白质和酶可以和新制备的磁体共价连接。
It has been shown that proteins and enzymes can be bound covalently to freshly prepared magnetite in the presence of carbodiimide.
需进一步深入研究方能解决共价键的起源问题。
Further study is needed before the origin of the covalent bond can be considered a settled question.
组蛋白是染色质的核心，其尾部共价修饰在基因表达调控中有重要作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
最常见的例子是有机化合物，亚硝酸盐类的同分异构体，其中一个碳原子以共价键与硝基中的氮原子结合。
The most common examples are organic compounds, isomers of nitrite esters in which a carbon atom is linked by a covalent bond to the nitro group's nitrogen atom.
因此，电子自旋配对不是共价键形成的原因，也不是先决条件，电子自旋配对只是双电子共价键的一个特点。
Therefore, the spin pairing is not cause of the formation of covalent bond, it is not also condition of first determining, the spin pairing is the only particularity of covalent bond of two electrons.
结果表明，高温超导材料属于具有部分离子性和部分共价性的晶体。
It shows that the high Tc superconductors are the crystals with both ionic and covalent properties.
过氧化物：任何由两个氧原子以单个共价键相互结合在一起的一类化合物。
Peroxide: Any of a class of chemical compounds in which two oxygen atoms are linked by a single covalent bond.
建立在混合轨道上的含有共价因子的能量矩阵称为广义能量矩阵。
The energy matrix constructed on the mixed wave functions and including the covalent factors is called generalized energy matrix.
本文研究了通过表面活化点放大来增加聚氨酯（PU）表面共价结合的肝素量的方法。
A method to immobilize heparin (Hep) covalently on the surface of PU by amplifying surface reactive sites was reported.
蛋白和配体间的作用通常是通过弱非共价键力的相互作用而实现的，如疏水作用、范德华力和氢键。
The binding of ligands to proteins occurs mostly through weak non-covalent interactions, namely hydrophobic interaction, van der Waals forces, and hydrogen bonding.
结论ESI-MS是研究药物与蛋白间非共价结合的一种新方法，具有灵敏、快速和准确的特点。
CONCLUSION ESI-MS is a new method for studying the drug-protein noncovalent binding, and it offers some advantages in sensitivity, high-speed, accuracy.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
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