这时,三分之一的候选药物通不过这个试验。
At the moment, a third of drug candidates do not pass such trials.
通过筛选法测定候选药物在体外,宿主细胞以及动物模型中的抗病毒活性。
Drug candidates are tested for antiviral activity using screening assays in vitro and host cells, as well as in animal models.
这些是用于开发具有较少不良反应潜力药物同时还兼具广泛抗hbv活性的候选药物利好。
These are broadly active anti-HBV candidates to develop drugs potentially with less adverse effects.
该平台为客户的候选药物开发发挥了关键作用,贯穿药物早期发现至临床前和临床全流程。
This platform has played a critical role in successfully advancing agents from early discovery to preclinical and clinical development phases for Pharmaron's partners and collaborators.
新的候选药物的一个重要的里程碑,因为它们是第一个分子都被设计法对基因控制老化过程。
The new drug candidates represent a significant milestone because they are the first molecules that have been designed to act on genes that control the aging process.
我们有两个后期临床候选药物,每个阶段2令人信服的数据,我们认为已经进行相当赞赏一段时间。
We have two late-stage clinical drug candidates, each with compelling phase 2 data, that we believe have been under appreciated for quite some time.
NRGN可能是一种候选药物靶标,因为它显然在调控记忆和认知方面很重要,这些过程常常在精神分裂症中被扰乱。
NRGN may be a candidate drug target, as it appears to play an important role in regulating both memory and cognition, processes that are often perturbed in schizophrenics.
作为心血管疾病主任,她负责项目领导,提供了多种临床试验前候选药物,其中有一些目前正用于临床研究。
As director of cardiovascular diseases, she provided project leadership for delivering several preclinical drug candidates, a few of which are currently in clinical studies.
目前确定候选药物出现此类相互作用可能性的主要方法是通过体外CYP450诱导和抑制潜能的快速筛选。
A rapid in vitro assessment of CYP450 induction and inhibition is a part of the current paradigms for identifying drug substances likely to be metabolized via such interactions.
结论川芎嗪是已知具有扩张血管、促进微循环的药物,其对肌梭的兴奋作用,使其有可能成为缓解失重性肌萎缩的候选药物。
Conclusion it is known that ligustrazine can expand blood vessels and agitate microcirculation, and this effect on the muscle spindle makes it helpful for persons with muscle atrophy.
尽管在临床前试验中抗生素格尔德霉素表现出很强的作为抗癌药物的潜力,但是因为其毒性,这种药物没有能成为具有良好临床试验前景的候选药物。
Although there was much preclinical interest in the antibiotic geldanamycin as an anti-cancer drug, it turned out to be a poor candidate for clinical trials because of its toxicity.
融合素的候选先导药物是西夫韦肽,一种HIV融合抑制剂。
The lead drug candidate in FusoGen's pipeline is Sifuvirtide, an HIV fusion inhibitor.
这种蛋白质被称为"肽适配",可以用于寻找候选的新药物。
Such proteins are called peptide aptamers and are used to find drug candidates.
而且,没有MCH而被饲养的小鼠保持瘦的体型并能够生育——这也可能使其成为大受欢迎的候选抗肥胖药物。
And mice bred without MCH remain lean - and fertile - which has made it a popular candidate for anti-obesity drugs as well.
你的医生将可以告诉你,如果你是候选人为这些药物。
Your doctor will be able to tell you if you are a candidate for these medications.
因为有威康信托药物开发基金的支持,该小组已确定了临床前的候选人,他们希望在一年之内进入人体试验。
With support from a Wellcome Trust Seeding Drug Discovery award, the team has identified a preclinical candidate that they hope to take into human trials within a year.
这些被抑制和被激活的蛋白可能为肿瘤生物标志物和药物作用靶点,为肿瘤的诊断和治疗提供了新的候选蛋白。
These repressed or activated proteins were the potential tumor biomarkers and drug targets, which would offer the candidate proteins for tumor diagnosis and treatments.
摘 要?目的:研制抗肝癌干细胞的功能性单克隆抗体,为肝癌干细胞的靶向治疗提供候选抗体药物。
Objective:To prepare functional monoclonal antibodies(McAbs) against liver cancer stem cells, so as to provide candidate antibody drugs for stem cell-targeted therapy of liver cancer.
在MLL白血病一个临床前鼠模型中,抑制GSK3可提供有效性的令人鼓舞的证据,并标记了GSK3作为候选的癌症药物靶点。
Inhibition of GSK3 in a preclinical murine model of MLL leukaemia provides promising evidence of efficacy and earmarks GSK3 as a candidate cancer drug target.
备注:如果候选人为分析化学或药物分析专业,并且成绩优异,那么应届毕业生也可以。
Note: If candidate majors in Analytical Chemistry or Pharmaceutical Analysis and is with good academic performance, the graduating college students are acceptable.
Ray表示:“这真是一个好事情,短肽的作用靶点恰好是一个非常保守的区域,非常有希望成为药物候选。”
"The really good thing is that it targets a very conserved area," says Ray. "it does seem to be a promising candidate."
它是Opko候选的主打药物。Opko是一家迈阿密公司,由建立了基因药物公司Ivax的亿万富翁PhillipFrost经营。
It is the lead drug candidate for Opko, a Miami start-up company run by Phillip Frost, the billionaire who founded the generic drug company Ivax.
它是Opko候选的主打药物。Opko是一家迈阿密公司,由建立了基因药物公司Ivax的亿万富翁PhillipFrost经营。
It is the lead drug candidate for Opko, a Miami start-up company run by Phillip Frost, the billionaire who founded the generic drug company Ivax.
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