通过磷酰氯与手性仲胺的亲核取代反应高产率地合成了手性HMPA 类似物。
The chiral HMPA analogues were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.
把亲核剂的亲核性和碱性的区别与相同之处进行了比较。
It compares the nucleophilicity of nocleophilic reagent with the similarities and differences of basicity.
胺能参加与卤代烷的亲核取代反应。
Amines can engage in nucleophile substitution reaction with alky.
从电性角度讨论了有机物分子的亲电性和亲核性问题，并阐述了两者在有机合成中的应用。
In this paper, electroaffinity and nucleophilicity of organic compound have been investigated, and their application in organic synthesis also has been discussed.
探讨碱性、溶剂极性、离去基团、吸电子基团、亲核试剂的亲核性对反应影响。
There are impact factor to be discussed such as solvent polarity, nucleofuge, attract electron group the nunucleophilicity of nucleophilic reagent.
涉及36的这种逐步亲核取代是不大可能的。
A stepwise nucleophilic displacement involving 36 was highly unlikely.
根据实验结果，我们推测反应的关键步骤为亲核进攻。
According to the experimental results, it was assumed that the cyclization was taken by nucleophilic attack.
并且对亲核试剂的体积效应、溶剂效应对亲核性影响，底物上吸电子基团的数目、吸电子能力对亲电性的影响，以及亲核取代反应的发生部位受哪些因素影响进行探讨。
At the same time, discuss about the impact factor to nucleophilicity such as the number of attract electron group, ability of attract electron and the nucleophilic substitution reaction part.
以2,3 -二氯苯胺为原料，经3步亲核取代反应合成了阿立哌唑。3步反应的收率分别为83%，91%和90%；总收率68%。
Aripiprazole in overall yield of 68% was synthesized from 2, 3-dichloroaniline by a three-step nucleophilic substitution reaction in yield of 83%, 91% and 90%, respectively.
迈克尔反应是一个典型的亲核加成反应，一直是有机化学领域的一个研究热点。
Michael reaction is a typical nucleophilic addition reaction, is always an organic chemistry domain research hot spot.
将母体染料的中位氯原子用氨基试剂亲核取代，衍生合成了五个中位仲胺七甲川菁染料。
Five derivative dyes from the parent dyes were obtained by similar nucleophilic substitution reaction in which five primary amines were employed as the nucleophilic reagent.
以磷酰氯为原料通过与手性仲胺的亲核取代反应高产率地合成了手性HMPA类似物。
The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.
本文比较了在甲醇介质下，2-苯基吲哚（1）单重态氧反应中的捕捉反应以及2-苯基-3H-吲哚-3-酮（4）的亲核加成反应特征。
Trapping reactions in singlet oxygenation of 2-phenylindole (1) and nucleophilic addition reactions of 2-phenyl-3H-indol-3-one (4) both in methanolic media were studied comparatively.
氢的替代亲核取代反应(VNS)是与硝基芳环的亲电反应、亲核反应不同的一种新反应。
Vicarious nucleophilic substitution (VNS) of hydrogen is a new type of reaction which is different from the usual electrophilic and nucleophilic reactions of the nitro arenes.
季铵化反应是一类重要的SN2亲核取代反应，溶剂对该反应的影响很显著。
Quaternarization is an important SN2 nucleophilic substitution reaction; solvent has remarkable effect on it.
两条路线中关键的一步反应是芳胺和溴代化合物的亲核取代反应，一般这步反应产率很低，并且需要较长的反应时间。
The key step of the two routes is the reaction of nucleophilic substitution of aromatic amines and -bromo compounds. Generally the produce rate of this reaction is low and the reaction time is long.
极性转换的本质是有机化合物反应中心碳原子电性发生转换，即亲电性或亲核性发生转换的过程。
The essence of polar conversion is that organic compound reflects the carbon atom electricity in the centre and changes, kiss the electricity or kiss the core course changing.
亲核性芳香取代。多取代苯衍生物合成的策略。
Nucleophilic Aromatic Substitution. Strategies in the Synthesis of Multisubstituted Benzene Derivatives.
考察了微波技术、反应物料比、催化剂以及溶剂等主要条件对亲核取代反应和产物收率的影响。
The effect of process conditions, such as microwave, reactant ratio, catalyst and solvent etc, on the nucleophilic substitution and yield of product were investigated.
反应机理推测为丝、苏氨酸的侧链基团羟基在咪唑的存在下亲核进攻磷原子形成五配位中间体。
Only N-phosphoryl serine and threonine methyl esters were catalyzed by imidazole, A new type of pentacoordinate phosphorus intermediate was proposed.
在B3LYP/6-311G计算所得的平衡几何构型基础上，分别根据静电势和分子轨道计算研究了分子中-NH2和-N（CH3）2的亲核性，并与偏二甲基肼和卤代烃反应的实验结果进行了对比分析。
On the basis of equilibrated geometrical structure obtained by B3LYP/6-311G method, the nucleophilicity of-N(CH3)2 and-NH2 groups are investigated by electrostatic potential and MO calculations.
利用氨基乙腈及丙烯腈的亲核加成、氢化反应合成了一种新的不等臂有机多胺化合物2 -氨基乙基-二（3-氨基丙基）胺。
A new inequilateral organic polyamine, 2-aminoethyl-bi(3-aminopropyl)amine, was synthesized by the additional and hydrogenation reaction of aminoacetonitrile with acrylonitrile.
前言：结合双分子亲核取代反应机理，对乙醇和盐酸反应过程进行分析，合理确定了工业生产乙基氯的工艺路线。
Combine with the"S N2 "mechanism, after analyses the reaction process of alcohol and hydrochloric acid, we reasonably determined the industrial process for the production of Ethyl chloride.
氨基- 1,2,4 -三唑与苦基氯的亲核取代反应动力学研究。
Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.
含活性基团的醛可与烯丙基碘和锡粉直接进行亲核加成反应，得到高烯丙基型的醇。水的存在不利于此反应的进行。
Aldehyde containing functional groups can react with allyl iodine and tin directly, water is of no advantage to the reaction.
在我们的合成方法中，先从-苯乙醇开始合成了-苯乙基氯，再用丙二酸二乙酯的烯醇盐离子进行亲核取代。
First we synthesized the -phenylethyl chloride from -phenylethyl alcohol. Then it was substituted by enolate anion of diethyl malonate and converted to ester.
在我们的合成方法中，先从-苯乙醇开始合成了-苯乙基氯，再用丙二酸二乙酯的烯醇盐离子进行亲核取代。
First we synthesized the -phenylethyl chloride from -phenylethyl alcohol. Then it was substituted by enolate anion of diethyl malonate and converted to ester.
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