目的研究二苯乙烯苷体外稳定性的特征。
Objective To study the features of stilbene glycoside's stability.
二苯乙烯苷；血管性痴呆；行为学；自由基代谢。
Stilbene glycoside; Vascular dementia; Behavioral; Free radical metabolism.
采用肝微粒体温孵和大肠杆菌培养等方法对二苯乙烯苷进行体外代谢研究。
Hepatic microsomal enzyme and culture solution of intestinal bacteria produced from rat feces were used for the research of metabolism of stilbene glycoside in vitro.
纯化后的产物经高效液相色谱分析，二苯乙烯苷含量达到70.34%，得率为64.13%。
The product concentration was 70.34% determined by HPLC, and the yield of the Stilbene Glucoside was 64.13%.
方法：硅胶柱色谱法，乙酸乙酯-石油醚梯度洗脱，自何首乌中提取分离二苯乙烯苷单体成分。
Methods: (1) to separate stilbene glycoside by using silica gel column chromatography with gradient elution consisting of ethyl acetate and petroleum ether.
方法：（1）以硅胶柱色谱法，乙酸乙酯-石油醚梯度洗脱，自何首乌中提取分离二苯乙烯苷单体成分。
Methods: (1)To separate stilbene glycoside by using silica gel column chromatography with gradient elution consisting of ethyl acetate and petroleum ether.
结果：模型组的NMDA受体结合力比假手术组明显升高，而二苯乙烯苷治疗组可以降低模型动物的NMDA受体结合力；
RESULTS Binding force of NMDA receptors of model group was significantly higher than that of sham operation group, while tetrahydroxystilbene treatment can decreased it significantly.
结果：模型组的NMDA受体结合力比假手术组明显升高，而二苯乙烯苷治疗组可以降低模型动物的NMDA受体结合力；
RESULTS Binding force of NMDA receptors of model group was significantly higher than that of sham operation group, while tetrahydroxystilbene treatment can decreased it significantly.
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