随着聚乙二醇基链长的增加，药物对乙酰胆碱酯酶抑制活性依次减弱。
With an increasing chain length of polyethylene glycol group linked on niclosamide, the inhibitory effects weakened.
摘要：采用微量筛选模型考察48种中药提取物的乙酰胆碱酯酶抑制活性。
Abstract: in this paper, the acetylcholinesterase (AChE) inhibitory activities of 48 traditional Chinese medicine extracts were investigated by microscale screening model.
本文利用簇合效应原理，合成了一些对乙酰胆碱酯酶抑制活性较好的化合物，为今后的研究工作提供了很好的基础，值得进一步深入开展这方面的研究。
In summary, we designed and synthesised some bivalent compounds as potential AChE inhibitors by cluster effect, the study provides a basis for the further related work and were worth further studying.
这些药物通过抑制在神经肌肉接合部位水解乙酰胆碱的乙酰胆碱酯酶的活性而发挥效应。
These drugs exert their effect by inhibiting the activity of acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the neuromuscular junction.
结论：硝基苯具有神经毒性，能够抑制肝和脑乙酰胆碱酯酶活性，且表现为明显的剂量效应。
We concluded that nitrobenzol is neurovirulent and it is able to inhibit the activity of cholinesterase in both liver and brain which displays evident dosage effect.
本发明涉及从蒲公英属植物中分离得到的一个木质素酸以及该化合物的强效抑制乙酰胆碱酯酶活性。
The present invention relates to lignin acid which is obtained by being separated from taraxacum plant and the strong activity of the compound of inhibiting acetylcholinesterase.
本发明的化合物具有抑制乙酰胆碱酯酶的活性，可期待作为防治老年性痴呆的药物用途。
The compound can inhibit activity of acetylcholinesterase and is expected to be used as a drug for preventing and treating senile dementia.
更多的研究表明乙酰胆碱酯酶抑制细胞的增殖是通过催化和降解乙酰胆碱的酶活性来实现的。
Further study showed that ACHE suppressed cell proliferation via its enzymatic activity of acetylcholine catalysis and degradation.
更多的研究表明乙酰胆碱酯酶抑制细胞的增殖是通过催化和降解乙酰胆碱的酶活性来实现的。
Further study showed that ACHE suppressed cell proliferation via its enzymatic activity of acetylcholine catalysis and degradation.
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