问:为何您在青蒿素耐药性并未引起关注的时候就研究青蒿素类复方药呢?
Q: Why did you research ACT for malaria at a time when there were no concerns about resistance to artemisinin?
另外,专家称,如果市场上只有青蒿素类的药品,一段时间以后最终还是会导致抗药性的出现。
What's more, public health experts say that the artemisinin-only pills on the market will inevitably engender drug resistance over time.
目前,疟原虫除了对青蒿素类未产生明显耐药性外,几乎对所有常规抗疟药都产生了抗性,然而新抗疟药的研制需要足够长的时间周期。
With the exception of artemisinin derivatives to which it has not yet developed marked resistance, Plasmodium has now developed resistance to almost all of the conventional anti-malarial drugs.
这是因为对最佳,也是最后一类有效抗疟药——青蒿素,产生耐药性所导致的失败。
This failure is due to resistance to artemisinin, our best and last class of effective antimalarials.
结果表明,与生理盐水对照组相比,青蒿素及其糖基化衍生物均可有效抑制肿瘤的生长和延长小鼠寿命,毒性实验表明属于低毒类物质。
Compared with normal sodium, the results showed artemisinin and its glycosylated derivates can suppress growth of tumor and increase in life span of mouse.
结果表明,与生理盐水对照组相比,青蒿素及其糖基化衍生物均可有效抑制肿瘤的生长和延长小鼠寿命,毒性实验表明属于低毒类物质。
Compared with normal sodium, the results showed artemisinin and its glycosylated derivates can suppress growth of tumor and increase in life span of mouse.
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