目的探讨胰高血糖素样肽2对放射损伤小鼠肠上皮恢复的影响。
Objective To investigate the effects of glucagon like peptide 2 (GLP 2) on recovery of small intestinal epithelia from radiation injury in mice.
结论胰高血糖素样肽- 2可促进放射损伤小鼠肠上皮的恢复。
Conclusion GLP-2 can promote recovery of small intestinal epithelia from radiation injury in mice.
胰高血糖素样肽- 1对胃排空、食欲和食物摄取的作用是否涉及人体中糊精的释放?
Do the Actions of Glucagon-Like Peptide-1 on Gastric Emptying, Appetite, and Food Intake Involve Release of Amylin in Humans?
本发明涉及胰高血糖素样肽-1受体的多肽类激动剂的体外筛选方法及筛选得到的多肽。
The invention relates to a multi- peptide agonist vitro screening method of the glucagon peptide-1 receptor and the screened multi- peptide.
目的本研究的目的是探讨人工甜味剂对人类葡萄糖、胰岛素和胰高血糖素样肽(GLP)- 1的影响。
OBJECTIVE the goal of this study was to determine the effect of artificial sweeteners on glucose, insulin, and glucagon-like peptide (GLP) -1 in humans.
目的制备载胰高血糖素样肽-1(GLP-1)的长效注射微球,并对其体外释放特性及药效学进行考察。
Aim To prepare glucagon-like peptide1(GLP-1) loaded long-acting injectable microspheres and to evaluate their in vitro release behavior as well as its pharmacodynamics.
BYDUREON和百泌达(BYETTA)都属于胰高血糖素样肽(GLP - 1)受体激动剂类药物。
BYDUREON and BYETTA belong to the glucagon-like peptide-1 (GLP-1) receptor agonist class of medications.
以往试图开发口服有效、具有胰高血糖素样肽- 1活性的小分子之努力均未成功,促使科研人员寻找其他途径。
Efforts to develop orally-available small molecules with GLP1-like activity have failed, leading researchers to search for alternatives.
目的探讨胰高血糖素样肽- 1 (GLP - 1)对软脂酸(PA)诱导的MIN6细胞凋亡及分泌胰岛素功能的影响。
Objective to investigate the effects of glucagon like peptide-1 (GLP-1) on palmitic acid (pa) -induced apoptosis of MIN6 cell lines and insulin secretion of MIN6 cell lines.
主要观察指标:口服50gr葡萄糖以后检测葡萄糖、胰岛素、胰岛素原、胰高血糖素、抑胃肽和胰高血糖素样肽- 1的水平。
Main Outcome Measures: glucose, insulin, proinsulin, glucagon, GIP and GLP-1 levels were measured after 50 gr oral glucose.
研究结论:这些数据显示胃旁路手术早期胰高血糖素样肽- 1和胰高血糖素的大量释放以及肠促胰岛素效应的增加和体重减轻没有关系而是和手术操作有关。
Conclusions: These data suggest that early after GBP, the greater GLP-1 and GIP release and improvement of incretin effect are related not to weight loss but rather to the surgical procedure.
王明伟和同事们通过对48,000多个化合物进行筛选,发现了两个颇有希望的候选结构。 它们能在细胞培养和活体动物模型上模拟胰高血糖素样肽-1的活性。
Ming-Wei Wang and colleagues screened more than 48,000 compounds and identified two promising candidates with the ability to mimic the actions of GLP-1 in cultured cells and in live animals.
王明伟和同事们通过对48,000多个化合物进行筛选,发现了两个颇有希望的候选结构。 它们能在细胞培养和活体动物模型上模拟胰高血糖素样肽-1的活性。
Ming-Wei Wang and colleagues screened more than 48,000 compounds and identified two promising candidates with the ability to mimic the actions of GLP-1 in cultured cells and in live animals.
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