• 右美沙芬的代谢表型研究为中国本地人的异丁喹4-羟化酶(CYP2D6)多态性提供了新的信息。

    Dextromethorphan metabolic phenotyping provides a new information for debrisoquine 4-hydroxylase (CYP2D6) polymorphism in native Chinese.

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  • 目的为了诊断和治疗21羟化酶缺乏导致的女性假两性畸形。

    Objective To diagnose and treat female pseudohermaphroditism caused by 21 - hydroxylase deficiencies.

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  • 根据苯酚羟化酶基因高度保守序列设计一对该基因的特异引物。

    A pair of specific primers of gene encoding phenol hydroxylase was designed by oligonucleotide high conservative sequence.

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  • 目的:探讨药物依赖行为和酪氨酸羟化酶在成瘾过程中的相互关系。

    AIM: To observe the relationship between the drug dependence behavior and levels of tyrosine hydroxylase (th) in drug acquisition process.

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  • 中文摘要:目的:建立清醒自由活动大鼠脑内酪氨酸羟化酶活性的测定方法。

    Objective: To set the measuring method of tyrosine hydroxylase activity in the brain of conscious rats.

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  • 目的对中国人非经典型21羟化酶缺乏症(21OHD)基因型进行研究。

    Objective To investigate the genotype in Chinese patients with nonclassical 21 hydroxylase deficiency (NC 21OHD).

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  • 在小鼠和烟草中,这是通过过渡表达聚羟化酶来实现的,类似于酵母和昆虫细胞培养。

    In mice and tobacco, this was overcome by over-expression of prolyl hydroxylase, analogous to what has been done in yeast and insect cell culture.

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  • 水杨酸羟化酶是细菌萘降解途径中的关键酶,它能催化水杨酸脱羟和羟化,生成儿茶酚。

    The salicylate hydroxylase, a important enzyme in bacterial naphthalene degradation pathway, catalyzes the decarboxylative hydroxylation of salicylate to form catechol.

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  • 羊水细胞DNA分析是先天性肾上腺皮质增生症21-羟化酶缺陷的产前诊断的可靠方法。

    DNA analysis of amniocytes was a feasible method for the prenatal diagnosis of congenital adrenal hyperplasia with 21-hydroxylase deficiency.

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  • 结论羊水细胞DNA分析是先天性肾上腺皮质增生症2 1羟化酶缺陷的产前诊断的可靠方法。

    Conclusion DNA analysis of amniocytes was a feasible method for the prenatal diagnosis of congenital adrenal hyperplasia with 21-hydroxylase deficiency.

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  • 目的:观察脑缺血后抑郁模型大鼠下丘脑酪胺酸羟化酶(TH)表达及益肾调气方药的干预作用。

    Objective:To observe the expression of Tyrosine Hydroxylase(TH) of Hypothalamus in post-stroke depression rat model and effects of Yishen Tiaoqi decoction.

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  • 这是首次用热不对称交错pcr法从木本植物的基因组dna克隆到类黄酮3'-羟化酶基因。

    This was the first time to clone flavonoid 3 '-hydroxy-lase gene from genomic DNA of woody plants by thermal asymmetric interlaced PCR.

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  • 目的分析19例21羟化酶缺陷症(21OHD)患者的临床和随访资料,提高该病的诊断和治疗水平。

    Objective Clinical data of 19 Chinese patients with 21 hydroxylase deficiency (21OHD) were analyzed to improve the diagnosis and treatment level.

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  • 目的探讨中国汉族人色氨酸羟化酶(TPH)基因A 218c多态性与单相抑郁症及其症状表型的遗传关联性。

    Objective to investigate the association among tryptophan hydroxylase (TPH) gene A218C polymorphism, unipolar depression (UPD) and symptom phenotypes in han nationality of Chinese.

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  • 结论:NURR1基因结合神经干细胞有效改善了帕金森病模型症状,提高移植后酪氨酸羟化酶阳性神经元细胞的数量。

    CONCLUSION: NURR1 gene combined with NSC can effectively ameliorate PD models symptoms and elevate the number of tyrosine hydroxylase positive neurons after transplantation.

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  • 增加EGR1表达可以激活其他信号分子的转录,包括CDK5和酪氨酸羟化酶,对神经细胞生长和分化有长期影响(2,3)。

    Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2, 3).

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  • 方法:采用免疫组化技术和高效液相-电化学法( HPLC - EC)分别对酪氨酸羟化酶(TH)、DA进行了含量测定。

    Methods: Immunohistochemistry technology and high-pressure liquid chromatography with electrochemical detector (HPLC-EC) were used to evaluated tyrosine hydroxylase (TH) and DA .

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  • 目的:研究内蒙古地区经典型苯丙酮尿症(PKU)苯丙氨酸羟化酶(PAH)基因突变的特点和频率,以提高该地区PKU的基因诊断率。

    Objective:To study the mutations of the phenylalanine hydroxylase(PAH)gene and enhance the gene diagnosis of classical phenylketonuria(PKU) in Inner Mongolia.

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  • 描述了包括总共具有15个组件的聚酮化合物合酶、具有1个组件的非核糖体肽合成酶和细胞色素P 450羟化酶组成的聚酮化合物合酶复合物。

    A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described.

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  • 描述了包括总共具有15个组件的聚酮化合物合酶、具有1个组件的非核糖体肽合成酶和细胞色素P 450羟化酶组成的聚酮化合物合酶复合物。

    A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described.

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