VHL基因可作为临床诊断指标,并可望成为肾透明细胞癌基因治疗的重要目的基因。
The VHL gene may be useful as a marker gene for the diagnosis of RCC and as a target gene for molecular therapy.
无论你具有遗传性还是获得性异常乳癌基因,如果你有一个正常基因,这个基因都仍将运行以控制细胞生长并预防基因。
Whether you inherited an abnormal breast cancer gene or acquired it, if you have one normal gene, that gene will still work to control cell growth and prevent cancer.
由于病毒可能会意外地启动细胞本身含有的致癌基因,因此这种方法生成的干细胞用在患者身上就不够安全。
Because the virus could accidentally switch on cancer genes, the cells would not be safe enough to use in patients.
他们发现母亲和婴儿的癌细胞携带有相同的突变癌基因(被称为BCR-ABL1),但是婴儿并没有得到这种基因的遗传。
They found the cancer cells of mother and baby carried the identical mutated cancer gene (called BCR-ABL1), but the infant had not inherited this gene.
研究人员在70年代早期取得了很大进展,他们发现导致癌症的癌基因在正常细胞里是不活跃的。
The researchers made great progress in the early 1970s, when they discovered that oncogenes, which are cancer-causing genes, are inactive in normal cells.
虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
上述试验是人工将癌基因导入肿瘤细胞株,另外的实验是在具有EGFR突变的肺癌肿瘤模型上进行。
Because the oncogenes had been artificially introduced into those cell lines, the researchers then tested their model in human lung cancer cells with the EGFR mutation.
致癌基因是一种可将健康细胞变成癌细胞的基因。
Oncogenes are genes that can cause healthy cells to transform into tumor cells.
初始细胞的癌基因的表达往往会通过诱导细胞凋亡、衰老来阻止细胞的增值的,而其实现上述功能的具体途径仍有待澄清。
Expression of an oncogene in a primary cell can, paradoxically, block proliferation by inducing senescence or apoptosis through pathways that remain to be elucidated.
肿瘤形成与控制细胞生长和分化的多种基因特别是癌基因、抑癌基因的遗传改变有关。
There are multiple genes especially oncogenes and tumor suppressor genes involved in 'the genetic alterations which regulating the growth and differentiation of cells.
人抑癌基因,其编码的蛋白,含有其的表达载体和由该载体转化的细胞。
Human cancer suppressor gene, protein encoded therein, expression vector containing the same, and cell transformed by the vector.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
科学家在芝加哥西北大学对乳腺癌细胞所作的实验表明,其中的关键成分是橄榄油中的油酸,油酸可以大幅度减少致癌基因。
Scientists at northwestern university in Chicago to breast cancer cells of the experiments show that the key component of the olive oil, oleic acid oleic acid is greatly reduced cancer genes can be.
干细胞白血病(SCL)基因是新发现的与白血病发生有关的癌基因。
The stem cell leukemia(SCL) gene is a new oncogene related with leukemogenesis.
目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。
It has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.
结论转染野生型PTEN抑癌基因能降低人高转移性黏液表皮样癌细胞转移能力。
Conclusion Transfection of wild-type PTEN tumor suppressor gene might significantly reduce metastatic ability of human highly metastatic mucoepidermoid carcinoma cells.
癌基因,肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
目的探讨外源野生型PTEN抑癌基因对人高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭特性的影响。
Objective To study effects of the exogenous wild-type PTEN tumor suppressor gene on in vitro adhesion, migration and invasion of the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
其作用机理为抗氧化作用,抗细胞增殖,诱导细胞调亡,干预细胞转导和增强抑癌基因表达,干预细胞周期等。
The mechanism are antioxidation, cell proliferation suppression, apoptosis induction, cell signal transduction disturbing and tumor suppression gene activity enhancing, cell cycle disturbing etc.
程序性细胞死亡因子4 (PDCD4)基因是首先在细胞凋亡中因一种表达特异的蛋白质而鉴别出来的一种新的抑癌基因。
Programmed cell death factor 4 (PDCD4) gene is a new anti-oncogene, which is firstly identified as a specific protein expressed in cell apoptosis.
干细胞白血病(CL)因是新发现的与白血病发生有关的癌基因。
The stem cell leukemia (SCL) gene is a new oncogene related with leukemogenesis.
目前有关癌基因的研究已不仅局限于肿瘤学,癌基因对正常细胞的生长、增殖、分化以及细胞内信息传递亦有重要意义。
Now the study on oncogene is not limited in oncology, and it is involved in cell survival, proliferation, differentiation and information transfer.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
EBV潜伏膜蛋白基因LMP1和核抗原基因EBNA2是公认的导致细胞恶性转化的病毒癌基因。
The EBV latent membrane protein (LMP1) gene and nucleoantigen gene EBNA2 are virus-oncogene, which can induce malignant transformation of cells.
原癌基因的突变导致的过度刺激细胞周期,而突变的肿瘤抑制基因,会导致在这一功能的控制过度活动。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
西班牙研究人员发现,橄榄油中所含的氨基酸能阻挠癌细胞繁殖,还可能削弱某种致癌基因的影响。
The Spanish researchers found, olive oil contain amino acids can obstruct the cancer cells to breed, may also weaken the effect of a cancer gene.
目的:检测癌基因d52家族新基因PC - 1在细胞周期各时相的表达变化。
Objective: To investigate the expression of PC-1, the new gene of tumor protein D52 family, during cell cycle.
目的:检测癌基因d52家族新基因PC - 1在细胞周期各时相的表达变化。
Objective: To investigate the expression of PC-1, the new gene of tumor protein D52 family, during cell cycle.
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