本发明涉及从阿德福韦制备阿德福韦酯二氧新戊酸双氧甲基酯的方法。
The invention relates to a method for preparing adefovir dipivoxil dual oxygen methyl pivalate from adefovir.
阿德福韦酯疗效发生缓慢，但耐药发生率低。
On the other hand, adefovir has a slow antiviral activity but with a lower rate of resistance.
阿德福韦治疗的持续时间为48周到240周。
The duration of adefovir therapy ranged from 48 to 240 weeks.
泰诺·福韦被广泛使用，人们担心会出现HIV的耐药菌株。
Tenofovir is widely used, and people are understandably concerned about the emergence of resistant strains of HIV.
现综述替诺福韦df的药理作用、药动学、临床试验和耐受性。
The pharmacological actions, pharmacokinetics, clinical trial and tolerance of tenofovir DF are reviewed in this article.
我认为有两个较为安全的选择：加用阿德福韦酯或改用替诺福韦。
I think the two safer options are to add adefovir with lamivudine or switch them to tenofovir.
治疗组给予加味五指毛桃汤口服，对照组给予阿德福韦酯胶囊口服。
Group was treated with oral soup flavored fingers peaches, control group was given capsules of oral adefovir dipivoxil.
目前研究的焦点是确定使用阿德·福韦5年治疗的安全性和有效性。
The focus of the present study was to determine the safety and efficacy of adefovir treatment for up to 5 years.
目的探讨阿得福韦酯治疗慢性乙型肝炎对患者血清纤维化指标的影响。
Objective To investigate the affection of Adefovir dipivoxil on the serum fibrosis marks in patients with chronic hepatitis B.
我们都非常期待替诺福韦能够通过药物批准，从而可以用于治疗这类患者。
We are looking forward very much to the licensing of tenofovir to be used in these patients.
卫生专家表示，这项研究的结果表明，替诺福韦凝胶可以增强女性的能力。
Health experts say the results of the study show that tenofovir gel can empower women.
一些人反对在杀菌剂中使用泰诺福韦，因为他们担心这会使艾滋病毒形成抗药性。
Some opposed tenofovir’s use in a microbicide because they worried that it would encourage the emergence of such resistance.
本文对检测阿德福韦双匹酯甲醇、乙腈和醋酸异丙酯残留量的方法学进行了研究。
This paper reports the text on the validation of determining procedures of these residual solvents in adefovir dipivoxil.
目的建立阿德福韦酯对照品含量测定的非水滴定法，以解决无商品标准品的难题。
Objective To establish a non-aqueous titration method to determine adefovir dipivoxil standard, and prepare the authentic sample of the compound.
值得注意的，每周两次AIC 649和每日两次替诺福韦的抗病毒治疗效果相同。
Noteworthy, the twice-weekly treatment with AIC649 showed an antiviral effect similar to the twice-daily treatment with Tenofovir.
建议使用毒性更小但效果相同的齐多夫定(AZT)或泰诺·福韦(TDF)作为替代品。
Zidovudine (AZT) or Tenofovir (TDF) are recommended as less toxic and equally effective alternatives.
但我们也要记住，替诺福韦和拉米夫定也都会出现在母乳中，不过其含量非常低，可能不会有太大影响。
Remember also, the drugs tenofovir and lamivudine both appear in breast milk but in very low levels and probably have little effect.
本发明涉及阿德福韦酯的制备方法，具体涉及到从阿德福韦制备阿德 福韦双特戊酸氧甲酯的制备方法。
The invention relates to a preparation method of adefovir dipivoxil, in particular to a method for preparing adefovir dipivoxil dual oxygen methyl pivalate from adefovir.
早期的研究已经显示，对慢性乙型肝炎e抗原阴性的患者进行48周阿德福韦治疗后，获得了临床上的改善。
Early research has shown that a 48-week course of adefovir provides clinical improvements in patients with HBeAg-negative chronic hepatitis B.
来自南非的科学家说，使用这种含有泰诺福韦的凝胶一年后的妇女感染艾滋病的机率比使用安慰剂凝胶低50%。
Scientists from South Africa say that women using the gel, which contained the drug tenofovir, had a 50 percent lower infection rate after one year compared to women given a placebo gel.
在制备阿德福韦酯的实验中，控制反应温度提高了反应产率，在减少了反应副产物的同时也使得产品提纯变得简便。
In the preparation of AD ester, we improve the yield by adjusting the reaction's temperature, make the byproduct fewer and also simplify the product's purification.
在制备阿德福韦酯的实验中，控制反应温度提高了反应产率，在减少了反应副产物的同时也使得产品提纯变得简便。
In the preparation of AD ester, we improve the yield by adjusting the reaction's temperature, make the byproduct fewer and also simplify the product's purification.
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