另外还发现该基因在癌化的猪肾上皮细胞中的表达量要比正常肾组织要高。
In addition, the higher mRNA expression was found in cancerization cell than the normal kidney tissue.
首先,他们发现,实验小鼠中癌化的肝脏细胞周围的细胞出现了老龄化的症状。
First, they found that the cancerous liver cells in their mice were generally accompanied by cells that had the symptoms of old age.
端粒和端粒酶是现代生物学研究的热点,端粒的缺失与细胞的衰老,端粒酶的活性与细胞的老化及癌化均有密切的关系。
Telomere and telomerase are the focus of modern biological study. There are close relationships among telomere loss and cell ageing, activation of telomerase, cell senescence and immortalization.
巴西一直信奉中间偏左的温和和多元化路线,鲁拉罹癌和DilmaRousseff在2009年罹患淋巴癌的细节都立即公诸于世。
In Brazil, which has espoused a moderate and pluralist vision of the centre-left, the details of both Lula's tumour and Ms Rousseff's cancer of the lymph in 2009 were made public immediately.
方法:应用免疫组化法检测乳腺癌及相应癌旁组织tlr4、增殖细胞核抗原(pcna)的表达,TUNEL法检测组织中细胞的凋亡。
Methods: the expression of TLR4 and PCNA in cancer tissues and adjacent tissues were assessed by immunohistochemical method and the apoptosis was detected by the TUNEL method.
关键在于应用在所有服药缓解非癌性疼痛而非癌性疼痛的患者身上的一个标准化项目上。
The key was having a standardized program applied to all patients who were getting the drugs for conditions other than cancer.
方法对19例肾嫌色细胞癌进行光镜观察、免疫组化研究及随访10~102个月,并复习相关文献。
Methods We examined the microscopic and immunohistochemical features in 19 cases of chromophobe cell renal carcinoma, followed up for 10 ~ 102 months and reviewed related literatures.
目的观察化瘀丸联合TC方案化疗对晚期卵巢癌的疗效及化疗毒副反应。
Objective To observe clinical effects and side reactions of Huayu pill combined with TC (Paclitaxel+Carboplatin) chemotherapeutic regimes on treating epithelial ovarian cancer.
目的为寻求贲门癌根治性手术的规范化,探索提高疗效的合理措施。
Objective In order to find out a normalization of cardial carcinoma radical surgery and a rational measures to improve the treating effect.
结论双重免疫组化染色法,可用于研究p 53与细胞角蛋白在鼻咽癌中的表达。
Conclusion the dual immunity group dyeing, may use in studying P53 and the cell keratin in pharyngeal cancer expression.
甲基化机制可能是肝细胞癌runx3基因失活的重要机制之一。
DNA methylation may be an important mechanism of inactivation of RUNX3 gene in HCC.
而癌周肝组织无论是肝硬化或肝纤维化均显示正常肝细胞的酶活性。
The surrounding liver tissue either in cirrhosis or in hepatic fibrosis appeared normal hepatic enzymatic activity.
目的检测皮肤基底细胞癌(BCC)中T钙黏蛋白的表达以及异常甲基化。
Objective To detect the expression and aberrant methylation of T-cadherin in cutaneous basal cell carcinoma (BCC).
目的:研究原发性肝细胞癌组织中总基因组DNA甲基化水平及其与病理学及生物学行为的关系。
Objective: To examine the extent of total genomic DNA methylation in hepatocellular carcinoma and the relationship between the DNA hypomethylation. and histopathologic characteristics.
结果支气管类癌尤其非典型类癌若无免疫组化的参与很易误诊为低分化癌或小细胞癌。
Results All the cases with atypical bronchial carcinoid tumor were diagnosed as low differentiation cancer without the help of immunohistochemistry.
方法用免疫组化的方法检测正常组织,癌旁组织和鳞状细胞癌皮损中hb EGF蛋白表达。
Methods HB-EGF in normal tissues, tissues adjacent to cancer and skin squamous cell carcinoma lesions were detected by immunohistochemistry.
方法取人直肠腺癌手术材料30例,用免疫组化方法检测癌区和癌周正常区vegf - C和VEGFR - 3的表达情况。
Methods Specimens were obtained from 30 patients with rectum adenocarcinoma, and examined for the expression of VEGF-C and VEGFR-3 in carcinoma region and normal region.
结论肝细胞癌中CHFR基因、EDNRB基因启动子的高甲基化是普遍现象,而3 -OST - 2基因启动子甲基化率较低。
Conclusion promoter methylation of CHFR and EDNRB genes is a common event in HCC, while frequency of promoter methylation of 3-ost-2 is rather low.
方法:应用免疫组化方法检测72例喉鳞状细胞癌组织标本中MMP-2和MMP-9蛋白的表达,并与临床病理特征和预后进行对比。
Methods: Immunohistochemistry was used to examine the expression of MMP-2 and MMP-9 in tissue samples of 72 LSCCs and the results were compared to clinical pathological features and prognosis.
嚼食槟榔已知为造成口腔白斑、口腔黏膜下纤维化、口腔癌及食道癌之主要危险因子之一。
The evidence of BQ chewing as one of the major risk factors leading to leukoplakia, oral submucous fibrosis, oral cancer and esophagus cancers have been well published.
MRI可辨别肺癌放疗后纤维化抑或肿瘤复发,区分肺门癌块与阻塞性肺不张;
MRI could distinguish porstradiotherapy lung fibroid masses from carcinoma recurrence and pulmonary neoplasm from obstructive atelectasis.
方法:运用甲基化特异性P CR,检测RASSF1A基因在48例喉癌组织、相对应癌旁组织及48例正常人外周血中的启动子区甲基化情况。
Methods a methylation-specific PCR was performed to detect the promoter methylation of RASSF1A gene in 48 tumor tissues, 48 corresponding normal tissues and 48 normal blood plasma.
目的总结作者应用肝部分切除联合肝十二指肠骨髂化治疗肝门部胆管癌的临床经验。
Objective to summarize the surgical experience of partial hepatectomy with skeletonization of the hepatoduodenal ligament in the treatment of hilar cholangiocarcinoma.
方法:运用PCR技术探查67例宫颈癌组织中HPV16感染率,并运用免疫组化ABC法检测HPV16感染对宫颈癌中E7蛋白表达情况。
Methods:PCR was used to detect HPV16 DNA in 67 samples of cervical carcinoma, the protein expression of HPV16 E7 were examined in HPV16 DNA positive samples through immunohistochemical ABC method.
目的观察鼻咽癌患者放疗后颈部纤维化的情况,探讨影响颈部纤维化的有关因素。
Objective to investigate the post-irradiation neck fibrosis in patients with nasopharyngeal carcinoma and its related factors.
为了降低人抗鼠抗体反应,获得满意的免疫原性,将模拟人卵巢癌抗原的抗独特型单链抗体人源化。
In order to reduce the human anti mouse antibody response and obtain optimal antigenicity, anti idiotype single chain which mimicking ovarian cancer antigen has been humanized.
采用免疫组化法检测60例肝癌组织及癌旁肝组织中vegf及MMP - 2的表达,用CD 34标记免疫组化法检测微血管密度(MVD)。
Immunohistochemistry was used to determine the expression of VEGF, MMP-2 in 60 HCC tissues and cancer adjacent tissues, and microvessel density (MVD) was detected with labelled CD34.
采用免疫组化法检测60例肝癌组织及癌旁肝组织中vegf及MMP - 2的表达,用CD 34标记免疫组化法检测微血管密度(MVD)。
Immunohistochemistry was used to determine the expression of VEGF, MMP-2 in 60 HCC tissues and cancer adjacent tissues, and microvessel density (MVD) was detected with labelled CD34.
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