这种新型的原理证明实验应该有助于创造患有人类疾病的转基因狗模型,该小组成员CheMyongKo说,CheMyong Ko所在的大学是列克星敦市的肯他基大学。
This new proof-of-principle experiment should open the door for transgenic dog models of human disease, says team member CheMyong Ko of the University of Kentucky in Lexington.
结论小型猪的混合唾液流率与人接近,是唾液疾病研究中较为理想的大型实验动物模型。
It is considered that minipig is a good large laboratory animal model for investigation of oral saliva gland diseases.
目前,这样的动物模型在实验研究中已经得以广泛应用,可助于研究人员更好地理解疾病的起因和寻找治疗的方法和药物。
Such mice, now commonly used in laboratory experiments, could help researchers better understand the origins of disease and find treatments and medicines.
牛血清白蛋白是一种球蛋白,目前已成功运用于血管性疾病实验动物模型的诱导及体外实验中。
Bovine serum albumin is one globulin, which has been successfully applied on animal models and vitro study on vascular disease.
同时他还说:“这个研究结果强调了这样一个事实——血脑屏障的通透性改变是发生象实验性变应性脑脊髓炎(一种多发性硬化病的动物模型)这类中枢神经系统感染性疾病的重要因素。”
"This puts an emphasis on the fact that blood brain permeability changes are an important aspect of the development of a CNS inflammatory disease like EAE, an animal model of MS," he says.
脊髓损伤是一种致残率很高的疾病,建立理想的脊髓损伤模型对于实验研究尤为重要。
Spinal cord injury is a kind of deformity disease with high incidence, so establishing an ideal experimental model of spinal cord injury is very important.
阻断整合素介导的白细胞黏附(尽管在实验模型中是有裨益的)在治疗人类的炎症性疾病上所获得的成功是有限的。
Blocking integrin-mediated leukocyte adhesion, although beneficial in experimental models, has had limited success in treating inflammatory diseases in humans.
结论椎间盘退变的动物模型是研究椎间盘退变性疾病发病机制的一种重要手段,同时为退变椎间盘的修复研究提供良好的实验载体。
Conclusion Animal model of intervertebral disc degeneration is an important path for revealing the pathogenesis of human disc degeneration, and play an important role in testing novel interventions.
结论椎间盘退变的动物模型是研究椎间盘退变性疾病发病机制的一种重要手段,同时为退变椎间盘的修复研究提供良好的实验载体。
Conclusion Animal model of intervertebral disc degeneration is an important path for revealing the pathogenesis of human disc degeneration, and play an important role in testing novel interventions.
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