蛋白质中的酪氨酰残基发生了明显改变。
多聚谷氨酰氨的聚集、沉淀可能是该病发病的原因和关键。
Therefore, inhibiting polyglutamine protein aggregation or deposition would be an important target for HD therapy.
这些发现提供了利用药物来阻碍门冬氨酰蛋白酶发挥作用的可能性。
The findings open the possibility of using drugs to block the action of plasmepsin V.
目的探讨l -丙氨酰- L -谷氨酰胺双肽的化学合成方法。
Objective To explore the method of chemical synthesis of L-alanyl-L-glutamine dipeptide.
目的建立甘氨酰脯氨酰二肽氨基肽酶（GPDA）自动化分析方法。
Objective To establish a kinetic monitoring assay for detecting glycylproline dipeptidyl aminopeptidase (GPDA). Methods Gly-pro-pNA.
提示断奶仔猪饲粮中添加甘氨酰谷氨酰胺二肽可提高仔猪的生长性能。
These results suggested glycylglutamine promotive effect on growth performance of the weaned piglet.
进一步获得了甲氨酰二氰基甲基阴离子作为桥联配体时的磁耦合信息。
The more magnetic coupling information dealing with Carbamyldicyanomethanideas bridging ligand was obtained.
结论：丙氨酰谷氨酰胺双肽在胃肠道术后经周围静脉tpn应用安全、有效。
CONCLUSION: It is safe and effective to use alanyl-glutamine dipeptide via peripheral vein TPN in patients after gastrointestinal operation.
目的：探讨甘氨酰脯氨酸二肽氨基肽酶（GPDA）在食管贲门癌组织中的变化规律。
Objectives:To explore the change rule and clinical value of glycylproline dipeptidyl aminopeptidase(GPDA) in tissues of esophageal and cardiac cancers.
目的探讨丙氨酰谷氨酰胺对慢性阻塞性肺疾病急性加重期患者(AECOPD)的治疗作用。
Objective To evaluate the value of alanyl glutamine in the treatment of aged patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
铜是人体必需的微量元素之一，是胎膜中胶原纤维发育成熟的关键酶赖氨酰氧化酶的活性辅基。
Copper is one of essential trace elements for human, acting as an active agon of lysyloxidase which is critical enzyme for collagen maturation.
目的：探讨血清甘氨酰脯氨酸二肽氨基肽酶（GPDA）活性测定对胃癌的诊断价值及方法学改良。
Objective:To study the improvement in method of testing activities of glycylproline dipeptidylaminopeptidase(GPDA) and its value in diagnosis of gastric carcinoma.
目的比较硫普罗宁(凯西莱)和鸟氨酰门冬氨酸(雅博司)在肝脏肿瘤患者围手术期护肝治疗的效果。
Objective To compare the hepatic functional protection of Tiopronin and Heperz applied during preoperative period in the patients with liver tumor.
目的研究尿甘氨酰脯氨酸二肽氨基肽酶（GPDA）诊断老年急性脑卒中患者早期肾损害的临床应用价值。
Objective To study the clinical value of glycylproline dipeptidyl aminopeptidase(GPDA) in diagnosis of early kidney injury in the elderly with acute stroke.
目的：为了解人肝癌组织及血清中甘氨酰脯氨酸二肽氨基肽酶(GPDA)同工酶变化，探讨其临床意义。
Objective: To study changes of GPDA isoenzyme in serum and hepatic tissues in patients with primary hepatic carcinoma and explore the clinical significance.
目的：观察胃肠道术后患者在经周围静脉全肠外营养（TPN）中应用丙氨酰谷氨酰胺双肽的安全性和有效性。
OBJECTIVE:To investigate the safety and efficacy of alanyl-glutamine dipeptide administered via peripheral vein total parenteral nutrition(TPN)in patients after gastrointestinal operation.
本文报道了以生色底物l -焦谷氨酰甘氨酰- L -精氨酸-对硝基苯胺盐酸盐为底物测定尿激酶效价的方法。
A method is reported for the determination of Urokinase potency using the chromogenic substrate L-pyroglutamyl-glycyl-L-arginine-p-nitroaniline hydrochloride.
结论实验组胶原分子聚合能力的改变，可能与腐殖酸对胶原分子中羟赖氨酰残基的糖苷化影响和胶原分子直径的影响有关。
Conclusions The influence of FA on the ability to collagen fibrillogenesis maybe caused by the changes of hydroxylysine glycosylation in collagen molecular and the diameter of collagen fibrils.
目的研究联合检测甘氨酰脯氨酸二肽氨基肽酶（GPDA）及其同工酶、腺苷脱氨酶（ADA）对不同性质腹水的鉴别诊断价值。
Objective To study the value of GPDA and its isoenzymes as well as ADA in the differential diagnosis of ascites.
天门冬酰胺酰甘氨酰精氨酸(NGR)是特异性地定位于肿瘤新生血管受体的多肽基序，在肿瘤诊断和治疗方面具有潜在的应用前景。
The NGR peptide is a ligand specifically binding to tumor angiogenic blood vessels, and thus has potential usage in the diagnosis and therapy of tumor.
目的探讨了血清可溶性白细胞介素-2受体（SIL-2R）和半胱氨酰白三烯（LTS）水平在支气管肺炎患儿治疗前后的变化及意义。
Objective To investigate the significance of changes of serum SIL-2R and cysteine LTS levels after treatment in pediatric patients with bronchopneumonia.
目的比较单乙基甘氨酰二甲苯胺（MEGX）肝功能试验和其余肝功能试验在预测外科重危监护（ICU）病人发生多器官功能衰竭（MOF）及预后方面的作用。
Objective To compare the sensitivity of the MEGX liver function test and conventional liver function test in predicting the risk of developing MOF and prognosis in ICU patients.
羧酸中的羟基被氨基取代后，生成的化合物，也可看作是氨的氢被酰基取代的衍生物。
The hydroxyl amino acid has been replaced, the resulting compounds can also be regarded as ammonia hydrogen has been replaced by acyl derivatives.
耐用聚酰氨携行具配尼龙带。
由此造成的疼痛的会很难受，可以给些药物刺激胃肠蠕动，如氨甲酰甲胆碱或甲硫酸新斯的明等。
The resulting pain can be so uncomfortable that medications to stimulate peristalsis, such as bethanechol or neostigmine methylsulfate, may be given.
用基于线性响应近似的自由能预测方法计算胰蛋白酶和苯酰氨类抑制剂的结合自由能。
Binding affinities of a series of benzamide inhibitors for trypsin were evaluated by molecular dynamics (MD) simulations using a linear response approach.
双相聚苯稀酰氨凝胶电泳（2DPAGE）与质谱（MS）是分辨和鉴定蛋白的最常用的方法，但也存在有缺点。
Two dimensional polyacrylamide gel electrophoresis(2D PAGE) followed by mass spectrometry(MS) is the most widely used method of protein resolution and identification. But it exist shortcomings.
本文采用基于线性响应近似的自由能预测方法计算了胰蛋白酶和苯酰氨类抑制剂的结合自由能。
The binding affinities of a series of benzamide inhibitors with trypsin were evaluated by molecular dynamics (MD) simulations with a linear response approach.
本文采用基于线性响应近似的自由能预测方法计算了胰蛋白酶和苯酰氨类抑制剂的结合自由能。
The binding affinities of a series of benzamide inhibitors with trypsin were evaluated by molecular dynamics (MD) simulations with a linear response approach.
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