• 目的阐明药物概念及其研究实际意义

    Objective: Expound chirality with chiral drugs concept and actual meaning of research.

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  • TANK正准备引怪加盾是性的错误而且我们并不打算修正

    Shielding the tank right as he's pulling is a rookie mistake, and we're not really trying to "fix" that.

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  • 可是,在生物化学界占支配地位,恰恰这样一种往往只能接受某一精密工具

    But the enzymes that govern biochemistry are such precise tools that, often, only one-handedness is acceptable.

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  • 比如说几乎所有构成生物蛋白氨基酸都是所以出现右自我复制生物分子可能意味着发现了外星生物体

    Almost all amino acids that make up biological proteins, for instance, are left-handed, so a self-replicating biological molecule of right-handed chirality could be suggestive of an alien organism.

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  • 许多药物分子性的并且两种象结构在药理上(pharmalogically)有所区别,对人体作用是不同的”,科恩

    "Many drug molecules are chiral and the two mirror images are pharmalogically different and do not have same interactions with the body," says Cohen.

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  • 通过磷酰核取代反应高产率地合成了手性HMPA 类似物

    The chiral HMPA analogues were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.

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  • 研究重氮烯向前手性烯烃单侧非对选择转移

    Diastereoselective transfer of the diazene hydrogen to one face of the prochiral alkene was studied.

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  • 用于合成各种具芳类结构的手性药物。

    It can be oriented to produce levo-aromatic and dextro-aromatic alcohols.

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  • 早期地球似乎并不存在手性偏好有机分子覆盖

    Early Earth seems to have been covered in a soup of organic molecules with no chiral preference.

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  • 确实认为可能发现其他结构来应用电子学应用中,前提确认就是自旋过滤发生机制

    But he does think that other chiral structures could find application in spintronics - if chirality is found to be the mechanism behind the filtering, that is.

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  • 此外如果分子很多手性中心一个都能起作用,那么所需分子结构产量很少

    Moreover, if there are lots of chiral centres in a molecule, and each matters, the yield of the version with the right combination can be minuscule.

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  • 脂肪酸没有手性它们的镜像分子就是自己。

    The fatty acids have no chirality; their mirror image is the same molecule.

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  • 表示,以科学工作者秉承谨慎态度来看,很难想象完全手性反转分子结构形成的镜像细胞成为现实

    The cautious scientist in him can’t see how the mirror cell, once full of chirally flipped molecular machinery, will come to life.

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  • 这种细胞的生物化学运作过程和普通生命完全一样——从DNARNA再到蛋白质,但手性对应的地球生命可能完全不相容

    Its biochemistry would work just like ours-dna to RNA to proteins-but it would be completely incompatible with earthly life, its chiral twin.

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  • 问题在于丘奇实验室与正常的设定匹配

    The problem for now is that Church's entire lab is tuned to the wrong chiral setting.

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  • 镜像方式对称分子通常具有不同,于是研究人员利用这种(chirality,译注:指分子的左/右螺旋质)”设计药物

    Molecules often come in mirror images that can have different properties, and researchers take advantage of this "chirality" to design new drugs.

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  • 基因基础但是同人的其他特征——身高体重——一样,十分复杂,”,“单独一个基因不能导致环境因素在其中很大作用。”

    "Handedness has a genetic basis, but like other complex traits - height, weight - it is complex," he said. "it's not a single gene that leads to it."There's a strong environmental component, too.

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  • 基因基础但是同人的其他特征——身高体重——一样,十分复杂,”,“单独一个基因不能导致环境因素在其中很大作用。”

    "Handedness has a genetic basis, but like other complex traits - height, weight - it is complex," he said. "it's not a single gene that leads to it." There's a strong environmental component, too.

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  • 为了形成这种光束他们绿色激光束照射反射镜上使原光束与其反射手性光束相互作用

    To make it, they shone a right-handed green laser beam at a mirror and let it interact with the left-handed reflection.

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  • 计划创造一种不但能阅读寻常rna转录体同时又将错误手性氨基酸串联起来形成镜像蛋白的核糖体。

    His plan is to make one that reads regular RNA transcripts of genes but can string together wrong-handed amino acids to form mirror proteins.

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  • 旋转偏振光他们用来筛选分子,这种电场以左螺旋形式空间旋进。

    They sort left from right versions using circularly polarised light, whose electric field corkscrews through space in a left or right-handed direction.

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  • 生物化学中,是有意义的,右旋物质气味可能不同

    In biochemistry, handedness can matter. Left - and right-handed versions may, for example, smell different.

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  • 但是手性始终是个比例——人群大约90%使用者,10%是左使用者——始终保持不变

    But the riddle of what underlies handedness remains. Its proportions - roughly 90 percent of people are right-handed and 10 percent left-handed - stay consistent over time.

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  • 就是为什么分别生产两种手性形式极其重要的。

    That is why it is vital to be able to produce the two chiral forms separately.

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  • 有朝一日国家主义主张反诉回漾冰川之上时,这一地区问题的刺手性迫使那些自诩的征服者们勉强共处。

    At a moment when nationalistic claims and counter-claims are resounding over the ice-floes, the region's intractability still forces its would-be conquerors to rub along.

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  • 实际上,根据Naaman解释手性分子蒸气过程作用主要—轨道耦合相互作用,显然而无法解释当前的实验结果

    As a result the interaction at work in the vapour - spin-orbit coupling - is simply too weak to explain these recent results, according to Naaman.

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  • 实际上,根据Naaman解释手性分子蒸气过程作用主要—轨道耦合相互作用,显然而无法解释当前的实验结果

    As a result the interaction at work in the vapour - spin-orbit coupling - is simply too weak to explain these recent results, according to Naaman.

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