目的本研究对所制得的芹菜素固体脂质纳米粒的制剂学性质和药动学进行研究。
OBJECTIVE To investigate the pharmacy characters and pharmacokinetic processes of the prepared apigenin loaded solid lipid nanoparticles (AP-SLN).
简要综述了中药中无机元素的分布及其存在形态，并探讨了一些制剂学因素对这两者的影响。
In this paper, the inorganic elements and their existent forms of traditional Chinese medicine were reviewed, the influence of some preparation factors on both of them were discussed.
但该药理化性质不稳定，水溶性差，胃肠道降解严重，口服无效，这给制剂学研究带来一定困难。
But the unstable physicochemical properties, poor solubility in water, severe degradation in gastrointestinal tract and ineffectiveness take orally which made the pharmacy research more difficult.
摘要：目的制备地西泮固体脂质纳米粒，评价其制剂学性质，并探讨其经鼻腔给药后的药动学过程。
ABSTRACT: OBJECTIVE To prepare diazepam solid lipid nanoparticles, evaluate the pharmacy characters and study the pharmacokinetics after intranasal administration.
为此，研究人员尝试通过制剂学手段对该类药物的水溶性及半衰期等参数进行改进，并获得了一定成果。
Recently, many scientists have been trying to improve the water solubility and half-life of these drugs by means of pharmaceutical methods, and have obtained the remarkable achievements.
对自我乳化药物传递系统的特点，形成机制，目前采用的处方组成等进行了综述，并对该系统的质量，影响因素及制剂学应用作了一般性介绍。
The characters, mechanism and formulation design of self emulsifying drug delivery system were reviewed. Its quality and affecting factors, and pharmaceutical applications were discussed.
生物危害一种生物制剂，如传染性细菌或对人类构成威胁的一疾病，尤指在生物学研究或实验中的。
A biological agent such as an infectious microorganism or a condition that constitutes a threat to human beings especially in biological research or experimentation.
结论不同型号的卡波姆凝胶具有不同的流变学性质，在制剂应用中应合理选用。
Conclusion the different types of carbomer have different rheological properties and they should be selected reasonably in pharmaceutical application.
目的：探讨制剂工程学实验教学的方法。
Objective: To study the methods of pharmaceutical engineering experiment.
结果：新的教学方式可应用于制剂工程学实验教学。
Results: Some new teaching methods would be practiced in pharmaceutical engineering experiment.
此外，鉴于肽核酸独特的理化和生物学性能，人们正尝试将其用于生物分子工具、反义和反基因制剂、分子探针和生物传感器。
In addition, the unique chemical, physical and biological properties of PNAs have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.
这些给药系统的口服制剂的组成和与药物相关的生物药剂学方面已经进行了广泛的研究。
The formulation and drug-related biopharmaceutical aspects of these systems that govern oral absorption have been widely studied.
目的：观察中药复方制剂仙脉通胶囊的对大鼠脑出血水肿模型行为学及相关细胞因子的影响，并讨论其作用机制。
Objective: to observe the effect of compound preparation cents Naomaitong capsule edema in rat model of cerebral hemorrhage and related behavioral effects of cytokines, and discuss its mechanism.
目的研究中药复方制剂三拗芎葶合剂对实验性低氧性肺动脉高压功能形态学的影响，并初步探讨其作用机制。
Objective To study the effect of San'aoxiongting mixture(SAXTM) on experimental hypoxemia pulmonary arterial hypertension and investigate its mechanism.
结果显示，家蚕雌蛾粉及其复方制剂具有明显的类雌激素生物学活性。
These results showed that female silkworm moth and it's compound preparation have the homologous estrogen biologic character in evidence.
结论药代动力学和药效学结果证明，三七总皂苷鼻腔给药制剂具有很好的开发前景。
Conclusion The results of pharmacokinetics and pharmacodynamics demonstrated that PNS intranasal preparation has a pretty prospect to develop.
端粒、端粒酶及其抑制剂研究是分子细胞生物学以及医学的热点之一。
Telomere, telomerase and its inhibitors are being extensively studied in the field of molecular and cellular biology and medicine.
血浆蛋白治疗制剂协会(PPTA)是最初的世界领先的血浆来源收集者的倡导者，它又是血浆衍生物和重组生物学疗法制造者的倡导者。
The plasma Protein therapeutics Association (PPTA) is the primary advocate for the world's leading source plasma collectors and producers of plasma-derived and recombinant biological therapeutics.
从生物药剂学的角度设计了“半仿生提取法”制备中药口服制剂的新工艺。
In the light of biopharmacy, the present new technology to extract oral preparations of Chimese traditional medicinal by semi-bionic method was designed.
本文通过分子生物学和生理生化两个角度对ALS抑制剂与ALS作用机理进行了初步的研究。
In this paper, the function mechanisms of acetolactate synthase (ALS) inhibitors to ALS had been carried out, using the methods of molecular biology, physiology and biochemistry.
新配方百白破混合制剂接种反应较低，血清学效果也较好。
The vaccination response of new absorbent pertussis mixed vaccine preparation was lower and its serological effect was better as well.
通过查阅国内相关资料，对金莲花属植物的分布、植物学研究、生药学研究、药理作用、临床应用和制剂工艺等方面进行综述性介绍。
This paper reviewed the distribution, botany studies, pharmacognostic studies, pharmacological effect, clinical applications and preparation processes of Trollius on the basis of related references.
观察免疫缺陷（损）者口服胸腺肽结肠溶制剂后的临床免疫学效果。
Purpose: The aim was to observe clinical effects of colonic-coated oral thymopeptidin on patients with immune deficiency.
目的为探讨血管形成抑制剂反应停对增生性瘢痕的治疗机制提供形态学依据。
RESULTS Treated with angiogenesis inhibitor thalidomide, the basement membrane of capillary became unintegrated, the endothelial cells degenerated, and the procedure of angiogenesis was damaged.
方法：通过多年教学实践，阐述开设制剂工程学实验的五种方式。
Methods:Based on years of teaching, 5 methods of the pharmaceutical engineering experiment were illustrated.
施用铜制剂还显著影响了土壤的生物学指标，表现为土壤基础呼吸和代谢熵升高，微生物生物量碳降低。
Moreover, the biological indexes of soil were affected, basal respiration and metabolic quotients were increased, microbial carbon was declined.
本试验旨在研究抗球虫中药制剂对肉鸡血清学指标的影响。
The experiment was conducted to study the effect of the Chinese herbal medicine against coccidian on the serum index of AA broilers.
认识药物代谢的酶学基础，了解药酶的常见底物、诱导剂和抑制剂，合理选用同类药品，能避免有害药物代谢性相互作用的发生。
The adverse drug interactions can be avoided by knowing the enzymology basis of drug metabolism, common substrates, inductors, inhibitors involved and using the same kind of drugs rationally.
目的：采用HPLC法建立快速测定大鼠血浆中阿苯达唑（ABZ）和阿苯达唑亚砜（ABZSX）的含量，为新制剂的处方筛选和药动学研究奠定基础。
Objective:To develop a rapid HPLC method for the simultaneous quantification of albendazole(ABZ) and its metabolite, albendazole sulphoxide(ABZSX), in rat plasma.
目的：采用HPLC法建立快速测定大鼠血浆中阿苯达唑（ABZ）和阿苯达唑亚砜（ABZSX）的含量，为新制剂的处方筛选和药动学研究奠定基础。
Objective:To develop a rapid HPLC method for the simultaneous quantification of albendazole(ABZ) and its metabolite, albendazole sulphoxide(ABZSX), in rat plasma.
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