将纯化的在大肠杆菌中表达的鹦鹉热衣原体(Cps)的重组主要外膜蛋白(MOMP)与油佐剂混合。
The purified recombinant major outer-membrane protein (MOMP) of Chlamydia psittaci (Cps) expressed in E. coli was mixed with oil adjuvant.
那么这个佐剂又是怎样起作用的呢?
生产商决定一种制品配方是否使用佐剂。
Manufacturers decide whether a product is formulated with or without an adjuvant.
目的研究双歧杆菌的免疫佐剂效应。
Objective To research the immunologic adjuvant effect of bifidobacterium.
使用佐剂是保持抗原持续存留的另一方法。
Another method of maintaining antigen persistence is through use of an adjuvant.
史特沃氏及其它清楚地表明碳链长度对安全佐剂的直接效果。
Stewarttull et al clearly show the direct impact of the length on the safety of adjuvants.
如条件适宜(如,使用新型佐剂),应利用动物模型开展生殖毒性研究。
Where appropriate (e.g. with use of novel adjuvants), reproductive toxicity studies using animal models should be conducted.
在过去的10年间,有大量的新型佐剂已被开发出来并已进行临床评价。
During the past decade, a large number of novel adjuvants have been developed and evaluated clinically.
这么规划的话,佐剂可以与任何引发流感爆发的病毒的抗原混合。
With such a plan, adjuvants will then be mixed with the antigen of whatever virus emerges as the pandemic strain.
角鲨烯本身并不是一种佐剂,但添加表面活性剂的角鲨烯乳剂可增强免疫应答。
Squalene by itself is not an adjuvant, but emulsions of squalene with surfactants do enhance the immune response.
在讨论安全问题时,需要对佐剂对免疫应答的影响及其作用机制有透彻的了解。
Safety issues will require a thorough understanding of the effects of adjuvants on the immune response and related mechanisms.
不明白这最古老的佐剂是如何发挥作用成了一个尴尬的话题和阻挡研究的障碍。
Not understanding how the oldest adjuvant of all does its stuff was thus becoming both an embarrassment and a barrier to further research.
Fauci博士说在孕妇的研究在9月开始,研究将使用一种佐剂以强化免疫系统。
Dr Fauci said studies in pregnant women should begin in September, as will studies using an immune system booster called an adjuvant.
短期和长期安全性评价和预测非常重要,同样重要的还有佐剂本身的药物代谢动力学评价。
Short-term and long-term safety evaluation and prediction are important, as is the evaluation of the pharmacokinetics of the adjuvant alone.
但这些抗原很难培养,研究人员正努力解决这个问题,通过使用增强剂或佐剂。
But they can be difficult to culture and scientists have been trying to fix that by using boosters, or adjuvants.
这是由于添加了黏膜免疫佐剂LTB的缘故,表明LTB能加强黏膜系统反应。
This is due to the addition of mucosal immunoadjuvant LTB. This indicates that LTB can enhance the mucosal system response.
在考虑佐剂安全性研究的框架时,一个引人注意的问题是缺乏动物模型来预测佐剂的安全性。
In considering a framework for safety studies of adjuvants, attention was drawn to the limitations of animal models in predicting adjuvant safety.
所有这些都需要一个在临床、科研和管理方面的新方法,来关注佐剂的短期和长期安全性问题。
All this requires a new clinical, scientific and regulatory approach, with attention to the short - and long-term safety of adjuvants.
角鲨烯本身并不是一种佐剂,但添加表面活性剂后的角鲨烯乳剂加入至抗原后可增强免疫应答。
Squalene alone is not an adjuvant, but emulsions of squalene with surfactants enhance the immune response when added to antigens.
疫苗安全咨询委员会邀请了更多的专家提交证据、资料和意见并参与讨论佐剂的安全性这问题。
The discussions on the safety of adjuvants took place with additional experts who presented evidence, information and opinion, and participated in the discussions.
WHO不久将推出一个针对佐剂临床评价的网站,内容包括佐剂的安全性及其临床试验的数据库。
A WHO web site on adjuvants in clinical evaluation including adjuvant safety, with a database of clinical trials, will be made available shortly.
本文综述鼻腔免疫应答的细胞和分子机理、抗原释放系统及佐剂等方面的最新研究进展。
We summarize the recent advances of the cellular and molecular mechanism, the delivery system of antigen and adjuvant of intranasal immunization.
有些大流行性流感疫苗含有佐剂以便减少病毒抗原的使用量(抗原是能够刺激免疫反应的一种物质)。
Some pandemic vaccines contain an adjuvant to reduce the amount of virus antigen to be used (an antigen is a substance capable of stimulating an immune response).
贮存效果不是唯一的装置,象弗罗因德氏佐剂那样证明在注射处切除材料而不抑止佐剂效应。
The depot effect is not the only mechanism as Freund have demonstrated that the excision of the material at the injection site does not suppress the adjuvant effect.
含佐剂的季节性流感疫苗以前主要是给老年人使用,因而我们目前还不清楚它在年轻人身上是否有副作用。
The seasonal flu vaccines with adjuvants have mostly been given to older people, so we cannot yet be sure that these vaccines do not have very rare side effects in younger people.
佐剂引起的不良反应事件应予记录和审阅,相关信息应可供查阅,在这方面世卫组织也应发挥其作用。
Adverse events attributable to adjuvants need to be documented and reviewed, and the information made available. That is another important role for WHO.
佐剂引起的不良反应事件应予记录和审阅,相关信息应可供查阅,在这方面世卫组织也应发挥其作用。
Adverse events attributable to adjuvants need to be documented and reviewed, and the information made available. That is another important role for WHO.
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