He seemed to be at his wits end before those ticklish questions.
面对那些棘手的问题他也显得束手无策了。
Unfortunately the study did not reveal any solution to parents at their wits end over the problem.
可惜的是，这项研究并没能告诉那些已经绞尽脑汁的家长们如何解决这个问题。
Now, do you also have times when you don’t love being a parent? Have you felt at your wits end, frustrated, angry and resentful?
你是不是也曾有这样的感觉：当你绞尽脑汁无计可施、沮丧、生气、愤 ..
Not everyone can find a great low-stress job quickly. If you're at wits end now, there are several ways to take the edge off your work situation.
并非每个人都可以很快找到一份低压的工作，如果你智穷计尽了，有很多方法可以帮你摆脱目前工作中的高压危机。
He was at his wits' end, having worked a year for nothing.
他哭不得笑不得，一年的气力白费了。
AT THE end of “Spirited Away”, Hayao Miyazaki's animated masterpiece, ten-year-old Chihiro uses her wits and her courage to escape from a nightmarish world of ogres and witches.
在宫崎骏的卡通名著《神隐少女》（又名《千与千寻》）中，故事的结尾十岁的小姑娘千与千寻凭借着她的智慧和勇气逃出了那个充斥着恶魔和巫婆的噩梦般的世界。
Even if the person may be at his/her wits-end handling the individual, just observing from a third party's point of view can give you insights on how to manage.
尽管他们对这些烦人的家伙一点辙都没有，但你只要以旁观者的视角观察，就会想到如何相处的方法了。
They reeled and staggered like drunken men; they were at their wits' end.
他们摇摇幌幌。东倒西歪，好像醉酒的人。
With all three children at home, the mother was at her wits' end trying to keep the house clean.
三个孩子全在家时，妈妈实在没办法把家收拾干净。
Why are so many traders at their wits' end, grappling with the obvious contradiction?
为什么很多交易者绞尽脑汁地和明显的矛盾斗争？
Unable to get a job when he left school, the boy lived by his wits and in the end turned to crime.
离开学校后没能找到工作，那个男孩靠小聪明过日子，最后走向犯罪。
I'm at my wits' end worrying about how to pay the bills.
我怎样付清这些帐，完全没有主意。
To tell the truth, I'm at my wits' end trying to figure out the problem with my computer.
我想找出电脑里存在的问题，但说实话，我已经一筹莫展了。
To tell the truth, I'm at my wits' end trying to figure out the problem with my computer.
我想找出电脑里存在的问题，但说实话，我已经一筹莫展了。
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