Cancer risk in chronic hepatitis B: Do genome-wide association studies hit the mark?
慢性乙肝的癌症风险：全基因组协会研究达到目的了吗？
The [new] study is small relative to the previous genome-wide association studies of coffee consumption, Cornelis said.
康奈利说：“新的研究和之前的全组基因与咖啡消费行为的研究相关甚微。”
The main course, however, is provided by three opinion pieces tackling the recent results of genome-wide association studies from quite different angles.
但主题来自于从不同角度对基因组相关性研究结果处理时产生的三种意见。
He added, “We have literally hundreds of genome-wide association studies for common diseases, and in most cases we are having trouble making much use of them.”
他补充说，“我们已经进行了许许多多的泛基因组研究，但是在大多数事例中，应用他们的时候都遇到了很多麻烦。”
The output of genome-wide association studies is vast, yet it is rarely straightforward to identify the functional connection between a variant and a disorder.
全基因组学关联研究所产生的数据结果是巨大的，但是很少能直接鉴别出突变和病症之间的功能关系。
Progress in understanding the genetic basis of atherosclerosis has come both from genome-wide association studies (GWAS) in populations and from focused studies of patients with extreme phenotypes.
人群全基因组关联研究（GWAS）和极端表型患者针对性研究均在理解动脉粥样硬化遗传理论方面取得了进步。
However, if it turns out that blood and tissue cells do not match genetically, these ambitious and expensive genome-wide association studies may prove to have been essentially flawed from the outset.
然而，如果血液和组织细胞在基因上原本并不一致，那么就证明那些雄心勃勃而又昂贵的全基因组相关的研究很可能一开始就有本质上的缺陷。
However, if it turns out that blood and tissue cells do not match genetically, these ambitious and expensive genome-wide association studies may prove to have been essentially flawed from the outset.
然而，如果血液和组织细胞在基因上原本并不一致，那么就证明那些雄心勃勃而又昂贵的全基因组相关的研究很可能一开始就有本质上的缺陷。
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