Valproic acid (VPA) is a compound of fatty acid and a commonly used anti-epileptic drug.
丙戊酸为一侧链脂肪酸类化合物，是临床治疗多种类型癫痫的一线药物。
Valproic acid (VPA) is often used to treat seizure disorder and mania as a mood stabilizer.
丙戊酸(VPA)常被用于治疗癫痫和躁狂症，是一种情绪稳定药物。
Aim To study the relation between dosage and serum concentration of valproic acid in children with epilepsy.
目的研究儿童癫痫服用丙戊酸后血药浓度与给药剂量的关系。
Taking L-carnitine supplements may prevent any deficiency and may also reduce the side effects of valproic acid.
以L -肉碱的补充防止任何缺陷，也可能降低丙戊酸的副作用。
And there's some evidence linking the use of prescription drugs — such as thalidomide and valproic acid — during pregnancy with a higher risk of ASDs.
此外也有证据表明怀孕期服用处方药如沙利度胺和丙戊酸会使婴儿面临较高的罹患asd的风险。
METHODS 156 epileptic outpatients received valproic acid as monopharmacy or in combination with either the antiepileptic drug were monitored during their clinical routine care.
方法对156例接受丙戊酸单药或联合用药治疗的门诊癫痫患者进行血药浓度监测。
OBJECTIVE To investigate the association between valproic acid (VAP) plasma concentration at steady state (Css) and CYP2C19 gene polymorphisms for better individualized medication.
目的：寻找丙戊酸药物浓度与CYP2C19基因多态性的关系，以便临床根据患者的基因型进行个体化给药。
Method: The serum concentration of oral phenytoin, carbamazepine and valproic acid were determined in 26,74 and 144 epileptic patients by fluorescence polarization immunoassay, respectively.
方法：采用荧光偏振免疫法对2 6例服用苯妥英钠、74例服用卡马西平、14 4例服用丙戊酸钠的患者血药浓度监测结果及临床疗效分析、评价。
OBJECTIVE: to observe the factors that influence the fluctuation of serum concentrations of valproic acid and to improve the effectiveness and usefulness of monitoring the serum concentration.
前言：目的：探讨影响丙戊酸钠血药浓度波动的因素，提高丙戊酸钠血药浓度检测的有效性及可利用性。
OBJECTIVE: to observe the factors that influence the fluctuation of serum concentrations of valproic acid and to improve the effectiveness and usefulness of monitoring the serum concentration.
前言：目的：探讨影响丙戊酸钠血药浓度波动的因素，提高丙戊酸钠血药浓度检测的有效性及可利用性。
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