• Remicade belongs to a class of drugs called tumor necrosis factor (TNF) blockers.

    Remicade属于被称为肿瘤坏死因子(TNF)阻断剂类药物。

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  • To assist in the diagnosis, those being treated with TNF blockers should tell their health care professionals where they live and what areas they have recently visited.

    为了有助于诊断,使用TNF阻滞剂的患者应该告知他们的健康保健专家自己住在什么地方和最近去过那些地点。

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  • We hypothesized that TNF induces opposing inflammatory and remodeling responses in HF that are TNF-receptor (TNFR) specific.

    我们的研究假设是TNF通过特异的TNF受体(TNFR)诱导相反的炎症和重构反应。

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  • Methods The serum content of TNF-a was detected by radioimmunoassay (RIA)in 20 healthy controls and 70 patients with malignant tumor.

    方法应用放射免疫测定法对20例健康对照者和70例肿瘤患者进行了血清TNF-a含量测定。

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  • Two groups were compared on the levels of serum tumor necrosis-a (TNF-a), interleukins-1 (IL-1) and IL-6 before and after the treatment.

    观察两组治疗前后血清肿瘤坏死因子、白细胞介素- 1、白细胞介素- 6的水平。

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  • The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2 (TNFRII) (4).

    首先鉴定出的TRAF家族成员是TRAF1和TRAF2,发现它们能够与TNF受体2 (TNFRII)的胞质结构域相互作用(4)。

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  • AIM: to explore the effect of TNF-related apoptosis inducing ligand (TRAIL), a new apoptotic inducing molecule on the biological activity of hepatocarcinoma cell line.

    目的:探讨新型凋亡分子TNF相关凋亡诱导配体(TRAIL)对人肝癌细胞系的作用及生物学活性的影响。

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  • Objective to investigate the role of tumor necrosis factor-a (TNF-a), norepinephrine (ne), endothelin (ET), adrenomedullin (ADM) in the pathogenesis of systemic inflammatory response syndrome (SIRS).

    目的探讨肿瘤坏死因子- a (TNF - a)、去甲肾上腺素(NE)、内皮素(et)、肾上腺髓质素(adm)在全身炎症反应综合征(SIRS)病理过程中的作用。

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  • A proliferation-induced ligand(APRIL)is a recently found member of tumor necrosis factor (TNF)superfamily.

    增殖诱导配体(APRIL)是近年来发现的肿瘤坏死因子(TNF)超家族成员。

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  • Objective: to observe the dynamic changes of tumor necrosis factor (TNF) in the animal MOF model and probe into the inner link of TNF and multi-organ failure (MOF).

    目的:在动物多器官衰竭(MOF)模型上动态观察肿瘤坏死因子(TNF)变化,探讨TNF与MOF的内在联系。

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  • Other risk factors were age, the first year of anti-TNF mAb treatment, and being born in an endemic area.

    其他的危险因素有年龄、抗TNF单抗治疗第一年及出生在结核流行区。

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  • Conclusions TNF, IL-6 and IL-8 play important roles in the physiological process of CHD and the measuring of these indexes may be a basis for diagnosis and prognosis in patients with CHD.

    结论TNF,IL - 6,IL - 8在CHD的病生理过程中起着重要作用,另外对这些指标的检测还可以作为CHD患者诊断、预后的一个依据。

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  • Recently some new medicines as anti-TNF bodies and T cell directed agents are used in treatment.

    近年来国际上对其治疗的研究已主要集中在分子水平上,如抗肿瘤坏死因子(TNF) 抗体,T细胞靶向药物等。

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  • Drugs recommended to be stopped before pregnancy include methotrexate and leflunomide, plus the biologics: anti-TNF agents, rituximab and abatacept.

    怀孕前应终止使用的药物包括甲氨蝶呤、来氟米特和一些生物制剂包括抗肿瘤坏死因子制剂、利妥昔单抗和阿巴西普。

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  • Conclusion: In situ hepatoma-specific gene therapy with IL-2 and TNF gene mediates anti-hepatoma immune response, but the mechanisms seem different.

    结论:IL - 2或TNF肝癌特异性原位基因治疗介导免疫抗肿瘤反应,但机理有所不同。

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  • The levels of soluble interlukin- 2 receptor (SIL-2R), tumor necrosis factor (TNF) , and interlukin- 6 (IL-6) were measured in 72 renal allograft recipients.

    检测了72例肾移植患者血中可溶性白细胞介素2受体(SIL-2R)、肿瘤坏死因子(TNF)及白细胞介素6(IL-6)的水平。

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  • Plasma endotoxin, serum TNF, IL-6 and IL-8 were detected at different time phase after burn.

    并在烧伤后不同时相点测定了血浆内毒素、血清TNF、血浆IL-6和血浆IL-8的含量。

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  • Keratinocytes of healthy persons and the patients with tumor or psoriasis can produce TNF. Meanwhile, TNF can affect the form and function of keratinocytes.

    正常人、肿瘤及银屑病患者的角质形成细胞均可以产生TNF, TNF又可影响角质形成细胞的形态和功能。

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  • Patients taking TNF blockers should be aware that they are more susceptible to serious fungal infections.

    使用TNF阻滞剂的患者应该注意到他们更易受到严重的真菌感染。

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  • Conclusion the plasma TNF level closely correlates with the complicated infectious shock and with the organ failure.

    结论血浆TNF水平与并发感染性休克或器官功能衰竭密切相关。

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  • Patients who develop a fungal infection may be advised to stop the TNF blocker until they recover.

    受到真菌感染的患者可能会被建议在真菌疾病康复前中止使用TNF阻滞剂。

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  • The FDA also has received reports of cases of coccidioidomycosis and blastomycosis, including deaths, in patients treated with TNF blockers.

    还收到一些使用TNF阻滞剂导致球孢子病和芽生菌病的报告,甚至还有死亡病例。

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  • Objective To study the effect of ischemic preconditioning on the apoptosis and the TNF plasma level.

    目的探讨缺血预处理对心肌细胞凋亡及血浆TNF水平的影响。

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  • TNF induced in the cell culture was demonstrated by monoclone antibody neutralizing test.

    诱生出的TNF通过单克隆抗体中和试验得到确证。

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  • Additional required updates to the prescribing information include incorporation of reports of psoriasis associated with the use of TNF blockers.

    要求更新的其他处方信息包括纳入与TNF阻滞剂使用相关的银屑病报告。

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  • TNF and insulin levels were highly correlated.

    肿瘤坏死因子与胰岛素水平有强相关性。

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  • The FDA also reviewed 69 cases of psoriasis and said it found a possible link between the skin disorder and use of TNF blockers.

    FDA也检查了69例牛皮癣,称皮肤病症和TNF拮抗剂之间可能存在某种的联系。

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  • Aim to study the effects of TNF receptor blocking peptide on adjuvant arthritis in rats.

    目的观察肿瘤坏死因子(TNF)受体封闭肽对大鼠佐剂性关节炎的影响。

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  • Conclusion: TNF gene may be correlated with the susceptibility of thymoma and thymoma with MG.

    结论TNF基因多态性与胸腺瘤发病及胸腺瘤发生重症肌无力相关。

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  • Conclusion: TNF gene may be correlated with the susceptibility of thymoma and thymoma with MG.

    结论TNF基因多态性与胸腺瘤发病及胸腺瘤发生重症肌无力相关。

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