In addition, they are divided into 6 groups according to target DNA elements they bind and their own structural characteristics.
此外,根据它们所作用DNA元件和自身结构特点又被分成6个组。
"Upon activation, these thousands of different transcription factors bind to their own specific target DNA sequence," said Ricci.
Ricci指出:“激活后,这几千种不同的转录因子即与其DNA序列特定靶标相结合。”
With availability of a fragment of target DNA sequence, flanking unknown DNA sequence was obtained rapidly by successive chromosome walk using Il-PCR method.
运用该技术进行染色体连续步移,快速扩增DNA侧翼未知序列。
Typical phages have hollow heads that store their viral DNA and tunnel tails with tips that bind to specific molecules on the surface of their target bacteria.
典型的噬菌体有存储它们病毒DNA的空心头部和带有尖端的隧道式尾巴,此尖端表面有它们的目标细菌的分子。
The team used zinc fingers that specifically target the IPK1 gene and then added bacterial DNA that would disrupt the gene while at the same time conferring herbicide resistance to the plant.
他们团队用利用锌指结构以IPK1基因为目标,另外添加可以中断此基因同时赋予植物抗除草剂性质的细菌DNA序列。
But it can take a long time for the right mutation to occur, especially if there is a very small target, like the region of DNA that controls a gene.
但要得到最合适的变异基因,耗费的时间会非常长,尤其是所要达到目标非常小时,如DNA中用来控制别的基因的区域部分,将是一项旷日持久的工程。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子,它可以EGR响应元素(ER),调节靶基因的表达(1)。
The researchers constructed the transposons in such a way that they can carry the therapeutic gene into the target cell DNA.
研究人员构建了转位子,通过转位子携带治疗基因进入靶细胞的DNA 。
The measurement target molecule with known concentration is used to perform the measurement, and the measured result is consistent to the added DNA quantity.
用已知浓度的检测靶分子进行测试,测定结果与加入的DNA量是一致的。
Once the target nanotubes are enveloped with the DNA, standard chemistry techniques such as chromatography can be used to separate them from the mix with high efficiency.
一旦DNA包裹目标纳米管,标准的化学技术(如色谱法)可从复合物中高效地分离出这些纳米管。
Results Artificial synthetic DNA transfer system and modified viral vectors could efficiently transfect target cells and get high level expression.
结果合成的DNA转运系统和经修饰的病毒载体体外转染靶细胞后,可获得显著表达。
At present, we consider NO released by activated macrophages can kill target cells by restraining the tricarboxylic acid cycle, electron transfer and composition of DNA in target cells.
目前认为,经激活的巨噬细胞释放的NO可以通过抑制靶细胞线粒体中三羧酸循环、电子传递和细胞DNA合成等途径,发挥杀伤靶细胞的效应。
Also we will hear more about novel delivery techniques for drugs such as small interfering RNA and antisense DNA whose primary target organ is the liver.
此外,还有更多有关新型药物运载技术的进展,如小分子干扰rna和反义dna,其主要的靶器官是肝脏。
CONCLUSION: In the construction of capillary DNA biosensors, EB can be taken as the fluorescent marker to detect the target oligonucleotide.
结论:在毛细管dna传感器构建中,溴化乙锭可作为荧光标记物对模式寡核苷酸进行检测。
Conclusion PNA combining with the DNA of target sequence had a highly specificity. Choosing PNA as the probe may improve the determined specificity of piezoelectric gene sensor.
结论PNA与靶序列dna结合有高度的特异性,选用PNA作探针,可提高压电基因传感器检测的特异性。
The Red mediated recombination can be used to insert, delete or substitute DNA sequences at any desired position on a target molecule without the need for restriction enzymes or DNA ligases.
这种技术可在DNA靶标分子的任意位点进行基因敲除、敲入、点突变等操作,无需使用限制性内切酶和连接酶。
Bystringing together several zinc fingers and adding a DNA-cleaving nuclease, researchers can precisely target specific genes to be cut.
通过将几个锌指出串联在一起,再加入一个切割dna的核酸酶,研究人员们能够精确地导向将被切割的特异性基因。
The aim of gene therapy is to transfect DNA into target cells, in which utilizing antisense oligonucleotides is a main method.
基因治疗是将DNA转染进入目的细胞,修复遗传错误或产生治疗因子。反义寡核苷酸的应用是基因治疗的主要手段之一。
This method can not only amplify DNA and RNA directly, but also allow the enlargement of signal from target nucleic acids with the sensitivity up to one copy of nucleic acids molecule.
这种方法不仅可以直接扩增DNA和RNA,还可以实现对靶核酸的信号放大,灵敏度达到一个拷贝的核酸分子,因此在核酸检测中具有很大的应用价值和潜力。
Short DNA sequences arrayed on substrates like glass, silicon or gold are used in biochemical sensors that can detect specific "target" sequences of DNA or analyze complex sequences.
排列在玻璃、硅、或金质的生化传感器片基上的短DNA序列,可用于检测特异DNA“靶标”序列或者分析复杂序列。
The expression of target gene being in said recombinant DNA in the new plant is controlled by proper chemical inducer.
在新的植物中该重组DNA中的目的基因的表达受合适的化学诱导物调控。
Liposome can bring the exogenous DNA into target cells because it will fuse with the cellular membrane easily.
这种脂质体一DNA复合物可以吸附于靶细胞表面,通过脂质体膜与细胞膜融合而将外源DNA 导人 纲胞内。
Pemetrexed is a multi-target anti-folate agents, by inhibiting the activity of enzymes which are necessary for folic acid synthesis to inhibit DNA replication and thus inhibit the tumor growth.
培美曲塞是一种多靶点抗叶酸制剂,通过抑制合成叶酸所必需的酶的活性来抑制DNA的复制从而抑制肿瘤生长。
Nur77 binds to specific DNA elements leading to the regulation of target genes (7).
Nur77结合到特定的DNA分子,导致靶基因的调控(7)。
It is an important biological target in the drug screening and drug designing. Lots of anticancer drugs and antiviral drugs had effects on DNA.
对DNA的研究是生命科学研究中一个极其重要的方面,在药物筛选和药物设计中它是重要的作用靶点。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
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