The complement system, where C4 resides, is known to play a key role in synaptic pruning in the brain, which occurs with normal aging.
在正常衰老过程中，包括C4在内的补体系统在脑突触修剪起重要作用。
Although C4 had long been known for its role in the immune system, the researchers found that it was also instructing this process of synaptic pruning.
C4在免疫系统中的作用已经为人们所熟知，但最新的研究发现它也控制突触修剪的过程。
"Babies are born with 100 billion neurons, " he says. "During the first years of life, some are salvaged and the others are left to wither. We call that synaptic pruning.
波尔穆特说：“婴儿出生时就有一千亿个神经细胞，在他们的婴幼儿时期，这些细胞中的一部分会被利用，其它的就任其退化死亡，我们把这一过程叫做突触削减。”
This synaptic pruning, as it is called, causes the brain's cortex-the outer layer of gray matter where we do much of our conscious and complicated thinking-to become thinner but more efficient.
我们称之为突触的自我修剪，保持意识清醒和用来复杂思维的大脑皮层，外面的灰质外层变得更薄但更高效。
This synaptic pruning, as it is called, causes the brain's cortex-the outer layer of gray matter where we do much of our conscious and complicated thinking-to become thinner but more efficient.
我们称之为突触的自我修剪，保持意识清醒和用来复杂思维的大脑皮层，外面的灰质外层变得更薄但更高效。
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