SV40 has long been used as a research tool to induce cancers in cell cultures.
SV40长期以来用作在培养细胞中诱导癌症的研究工具。
When SV40 enters a cell, it produces t antigen, which functions to trigger viral DNA replication.
当SV40病毒进入细胞时会产生T抗原，它的作用是触发病毒DNA繁殖。
Although the SV40 genome has been found in some human tumors, its role in human cancer has been debated.
虽然SV40的基因组也在某些人类的肿瘤中也发现过，但是对于它是否会引发人类癌症这一问题仍在讨论之中。
Objective to explore the SV40-mediated immortalization, the related factors and their roles in cell immortalization.
目的探讨SV40如何介导细胞永生化，与细胞永生化现象相关的因素及它们的作用。
Results showed that IRES was superior to SV40 promoter for guarantee of genes co expression in bicistronic retrovirus mediated gene therapy.
结果表明：在双基因逆转录病毒载体介导的小鼠骨髓细胞的基因转导中，IRES与内部SV40启动子相比，更能保证双基因的共同表达。
Therefore, an immortalized rat glial cell line (RGLT) was established by SV40 large T-antigen (LTag) gene from the primary rat fetal glial cells.
以SV4 0大T抗原转化原代大鼠原代胶质细胞得到的永生化胶质细胞（RGLT）可解决这些问题。
MethodsKidneys, lungs and spleens of 56 monkeys and 10 poliovirus vaccines were examined by PCR using designed three pairs of primers on SV40-776 sequence.
方法根据SV40 - 776株设计合成三对引物对现有毒株进行PCR扩增并克隆测序。用这三对引物对56份猴肾、肺、脾及10批脊髓灰质炎疫苗进行检测。
In vitro DNA replication system derived from eukaryotes is capable of replicating exogenous plasmid DNA containing SV40 origin of replication efficiently and accurately.
报道了含sv40复制起点的质粒dna在真核细胞抽提物中进行复制的DNA体外复制系统的建立。
In vitro DNA replication system derived from eukaryotes is capable of replicating exogenous plasmid DNA containing SV40 origin of replication efficiently and accurately.
报道了含sv40复制起点的质粒dna在真核细胞抽提物中进行复制的DNA体外复制系统的建立。
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