Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.
称之为肿瘤抑制基因的突变可以引起生长失去控制,从而可能导致癌症。
However when they injected the hind leg of mice with the CD47 suppressor, it showed much less hair loss, ulceration and peeling when targeted by radiation than an untreated leg.
但是他们发现,在给小鼠的后腿注射了CD47抑制剂后,脱发,溃疡和脱皮这些暴露在放射线下的副作用相比于没有注射CD47抑制剂的小鼠后腿减轻了很多。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
原癌基因的突变导致的过度刺激细胞周期,而突变的肿瘤抑制基因,会导致在这一功能的控制过度活动。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学:p53肿瘤抑制基因突变,第11p15基因座杂和性丢失。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学:p53肿瘤抑制基因突变,第11p15基因座杂和性丢失。
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