A study of tumor suppressor genes on chromosome 9 in glioblastomas.
胶质母细胞瘤9号染色体肿瘤抑制基因的研究。
There are enormous oncogenes and suppressor genes involved in cancer.
有巨大的癌基因和抑癌基因的癌症有关。
The advances in the study of tumor suppressor genes in gliomas were reviewed.
作者就目前在脑胶质瘤中研究较多的抑癌基因的进展作了综述。
Objective To clone tumor suppressor genes associated with human esophageal cancer (EC).
目的克隆食管癌缺失的基因。
In contrast, undifferentiated carcinomas rarely exhibit structurally altered tumor suppressor genes.
相反，未分化癌极少表现出抑癌基因结构的改变。
Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.
这种染色体异常使控制细胞生长的关键肿瘤抑制基因失活。
Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.
称之为肿瘤抑制基因的突变可以引起生长失去控制，从而可能导致癌症。
Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array.
目的：从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
Purpose: Ample evidence supports an important role of tumor metastasis suppressor genes in cancer metastatic processes.
目的：在肿瘤转移过程的研究中，许多证据已经证实了肿瘤转移抑制基因的重要性。
One approach, used by Shenzhen SiBiono GeneTech, a Chinese company, is to replace broken tumour-suppressor genes with the correct version.
一种由深圳赛百诺基因技术公司――一家中国公司，所使用的方法就是用正常的肿瘤抑制基因置换破损的肿瘤抑制基因。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
Tumor metastasis suppressor genes is a kind of genes that only suppresses tumor metastasis without affecting tumorigenesis and tumor growth.
转移抑制基因是一类只抑制癌细胞的转移但不影响肿瘤发生和生长的基因。
Identification and research on the oncogenes and the tumor suppressor genes will provide new targets of prevention and treatment to lung cancer.
鉴定和研究相关癌基因和抑癌基因的功能有望为肺癌防治提供新的靶标，因而一直是肺癌研究领域内的热点。
Aim: To evaluate the clinical value of MSP (methylation specific PCR) in detection of tumor suppressor genes methylation in the colorectal cancer.
目的：评价特异性甲基化pcr (msp)分析法检测抑癌基因高甲基化对结、直肠癌的诊疗价值。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
It could also inform cancer research, as it could give scientists the opportunity to reactivate tumor suppressor genes that had been silenced by DNA methylation.
通过去甲基化或重新激活DNA甲基化所沉默的肿瘤抑制基因，它们可能为干细胞重新编程和癌症研究提供非常重要的信息。
Quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis.
其中涉及多种基因异常，包括易感基因、癌基因、抑癌基因等，对于乳腺癌的诊断、治疗及预后判断均具有提示作用。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
虽然许多原癌基因和肿瘤抑制基因被广泛表达，这些基因的突变与特定的器官或细胞类型的癌有关。
The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.
癌基因和抑癌基因的发现，细胞信号传导通路的阐明，极大地丰富了人们对细胞癌变机制的认识。
There are multiple genes especially oncogenes and tumor suppressor genes involved in 'the genetic alterations which regulating the growth and differentiation of cells.
肿瘤形成与控制细胞生长和分化的多种基因特别是癌基因、抑癌基因的遗传改变有关。
Objective To explore the role and significance of apoptosis, pro-apoptotic genes and apoptosis suppressor genes in the pathogenesis and development of inhalation injury.
目的探讨细胞凋亡、促凋亡基因和凋亡抑制基因在吸入性损伤发生的作用及意义。
Oxidative stress can cause DNA damage, such as DNA strand breaks, point mutations, aberrant DNA cross-linking, and mutations in proto-oncogenes and tumor suppressor genes;
氧化应激可以导致DNA链断裂、DNA位点突变、DNA双链畸变和原癌基因与肿瘤抑制基因突变等形式的DNA损伤；
With the new technique, it is possible to identify potential tumour-suppressor genes from among the approximately 25,000 human genes and accelerate research significantly.
运用这种新技术，可以在大约25，000个人类基因中鉴别出肿瘤抑制基因，并且显著加快研究进程。
These observations suggest that the mutated tyrosine phosphatases are tumor suppressor genes, regulating cellular pathways that may be amenable to therapeutic intervention.
这些观察提示突变的酪氨酸磷酸酶是肿瘤抑制基因，它调节的细胞通路可能会被利用到治疗干预中去。
The genesis of gastric cancer resulted from abnormal expression of many genes, and methylation of the tumor suppressor genes is one of the major mechanisms of gastric carcinogenesis.
胃癌的发生与多基因异常表达密切相关，其中抑癌基因甲基化是胃癌发生、展的重要机制之一。
Conclusions FHIT and WWOX are candidate tumor suppressor genes. Detected coordinately with other (molecular) parameters, they can make the prognosis of therapy more accurate to predict.
结论FHIT和WWOX基因系重要的候选抑瘤基因，与其他预后指标的联合检测可望对患者的治疗预后作出更准确的预测。
The recent studies demonstrate that cytogenetic alterations, oncogenes, tumor suppressor genes, adhesion molecules and extracellular matrix proteins may play important roles in the process.
研究发现，细胞遗传学改变、癌基因、抑癌基因、黏附分子及细胞外基质蛋白在涎腺多形性腺瘤的恶变过程中均有一定的作用。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
原癌基因的突变导致的过度刺激细胞周期，而突变的肿瘤抑制基因，会导致在这一功能的控制过度活动。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
原癌基因的突变导致的过度刺激细胞周期，而突变的肿瘤抑制基因，会导致在这一功能的控制过度活动。
应用推荐