More intense monitoring will be required to determine potential stopping points should breakthrough occur providing an added layer of vigilance when using these drugs.
出现病毒学突破意味着已产生耐药应立即停药以避免进一步加深耐药。
Potential adverse effects include peripheral neuropathy, myopathy, lactic acidosis and severe hepatomegaly with steatosis, and - after the stopping treatment - worsening of hepatitis.
潜在的不良反应包括周围神经病变，肌病，乳酸性酸中毒和严重的肝肿大伴脂肪变性，以及-停止治疗后-肝炎恶化。
Potential adverse effects include peripheral neuropathy, myopathy, lactic acidosis and severe hepatomegaly with steatosis, and - after the stopping treatment - worsening of hepatitis.
潜在的不良反应包括周围神经病变，肌病，乳酸性酸中毒和严重的肝肿大伴脂肪变性，以及-停止治疗后-肝炎恶化。
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