There is positive correlation between peak and trough steady-state concentration and the body weight doses.
稳态血药浓度峰值和谷值与体重剂量呈正相关;
OBJECTIVE To investigate the association between valproic acid (VAP) plasma concentration at steady state (Css) and CYP2C19 gene polymorphisms for better individualized medication.
目的:寻找丙戊酸药物浓度与CYP2C19基因多态性的关系,以便临床根据患者的基因型进行个体化给药。
It is found that surface chloride ion concentration gradually grows with the of time increase the of time and reaches a steady state finally.
结果表明,表面氯离子浓度随时间的增加逐渐增长并最终达到稳定状态。
When VPA is administrated alone, the standardized plasma concentration at steady state (Csss) of VPA is higher in poor metabolism patients than that in normal metabolism patients ( P< 0. 05).
单一应用VPA时,弱代谢患者较正常代谢患者的VPA血药浓度有所升高(P<0.05)。
Useful information provided by steady state flow method can also be obtained from dynamic experiment as the concentration of the absorbed species on the catalyst surface changes with time.
在动态过程中,催化剂表面上的吸附物种浓度随时间而变化,从而可以获得稳态流动法所不能提供的信息。
The existence of L-Cysteine resulted in prolonging the lag time of the enzyme reaction, while the steady-state rate of the enzyme activity decreased with the increase of concentration of L-Cysteine.
实验发现L-半胱氨酸对该酶有明显的抑制作用,它的作用可以导致马铃薯多酚氧化酶的酶促反应的迟滞时间延长,同时使稳态酶活力下降。
All patients treated with vancomycin for 5 days or more should have at least 1 steady-state trough serum concentration measured just before the fourth dose.
所有患者万古霉素治疗5天或以上的,应至少有1稳态血药浓度槽前第四剂量测量。
It is important however to remain consistent with the chosen time, plus or minus one hour, in order to reach the steady-state and not have fluctuations in the concentration.
非常重要的是要与使用时间保持一致性,前后控制在一小时内,这样药物浓度可以达到稳定状态而无波动。
It is important however to remain consistent with the chosen time, plus or minus one hour, in order to reach the steady-state and not have fluctuations in the concentration.
非常重要的是要与使用时间保持一致性,前后控制在一小时内,这样药物浓度可以达到稳定状态而无波动。
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