• Aim In order to increase bioavailability of Artemisinin'S dosage form, solid dispersion of Artemisinin was prepared.

    目的:研制青蒿素缓释固体分散物,提高其制剂的生物利用度。

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  • In the production of coating, colorant, and filled plastics, the dispersion of solid particles in the agent directly determines the product quality.

    在涂料、颜料、填充塑料的生产过程中,固体颗粒在介质中的分散性能直接影响产品质量。

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  • The processes, characteristics, influence factors and applications of new technology for solid dispersion preparation are introduced.

    介绍了固体分散法制剂工艺的类别,及其特点、过程、影响因素和应用等。

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  • Objective: to investigate whether the combined carrier is superior to the single carrier in improving dissolution of poorly insoluble water drug and prepare a fast released solid dispersion.

    目的:考察水溶性联合载体在增加难溶性药物的溶出速率上是否优于单一载体,并制备速释型固体分散体。

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  • One dimensional sedimentation dispersion model simulates the axial distribution of solid holdup well.

    固含率轴向分布的一维沉降-扩散模型模拟值与实验值吻合较好。

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  • It is indicated that the solubility of Nisoldipine capsule is improved by the utilization of solid dispersion technology.

    结果证明,采用固体分散技术能提高尼索地平的体外溶出度。

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  • Droppills were made by solid dispersion technology with the bases of PEG4000 and PEG6000, which has established the optimum moulding craft.

    采用固体分散技术以聚乙二醇4000和聚乙二醇6000作为基质,甲基硅油作为冷却剂优化了滴丸成型工艺。

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  • Then the pretreated samples were extracted with acetonitrile, further cleaned up by reverse solid phase dispersion, and analyzed by reversed phase HPLC with diode array detector (DAD).

    韭菜样本用微波炉加热处理,使酶钝化消除含硫基质干扰,然后用乙腈提取、逆固相分散净化,用反相高效液相色谱-二极管阵列检测器检测。

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  • OBJECTIVE: to prepare tinidazole solid dispersion using the technology of solid dispersion, and to increase the dissolubility and the dissolution rate of tinidazole.

    目的:利用固体分散技术制备替硝唑固体分散体,增加替硝唑溶解度和溶出速度。

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  • The scattered solid, liquid, or gas in a dispersion that is surrounded by the continuous phase.

    被连续相所围绕的分散体系中的固体、液体或气体。

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  • OBJECTIVE To improve in vitro release of acemetacin, the technology of solid dispersion was used and acemetacin was prepared as solid dispersion.

    目的:利用固体分散技术制备阿西美辛固体分散体,增加其溶解度和溶出速度。

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  • Drilling cuttings dispersion is controlled and the penetration rate is improved because of the better performance of the solid control equipment.

    能抑制钻屑分散,有利于发挥固控设备效率和提高钻井速度;

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  • Method: Bomeolum Syntheticum and PEG 6000 mixing preparative solid dispersion and packed capsules, toxicity was tested.

    方法:将冰片用水溶性辅料聚乙二醇6000制成固体分散体,并填装入胶囊,进行毒理试验。

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  • Cefuroxime Axetil granules were prepared by solid dispersion technique with gelatin as the main materials for masking the bitter. The bitter after masking and the stability were investigated.

    采用明胶作为主要掩味材料,利用固体分散技术制备头孢呋辛酯颗粒剂,并进行掩味效果及稳定性考察。

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  • CONCLUSION Itraconazole solid dispersion can significantly increase it's solubility and dissolution rate.

    结论:伊曲康唑固体分散体能明显提高伊曲康唑的溶解度及体外溶出速率。

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  • The solid dispersion technology was employed in research and development of Nisoldipine capsule. Further more, the dissolution rate was detected upon the capsule.

    采用固体分散技术研究和制备了尼索地平胶囊,对其进行了溶出度测定。

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  • Fenofibrate solid dispersion tablets were prepared by solvent melting method using PEG4000 and sodium lauryl sulfate.

    PEG4000十烷硫酸钠体,溶剂-熔融制备非诺贝特固体散体,再适辅混合压片制非诺贝特固体散片。

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  • It is prepared by supercritical extraction, flocculating and alcohol settling cyclodextrin investing and solid dispersion preparation technique.

    该制剂的制备采用了超临界提取及絮凝醇沉的工艺及环糊精包埋与固体分散体制剂技术。

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  • Conclusion Etodolac solid dispersion can significantly increase the dissolution rate.

    结论依托度酸固体分散体能显著提高依托度酸的溶出速率。

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  • The increasing of conductivity is the decomposition of the supersaturate solid solution contain Sc and Zr forming dispersion complex phase.

    电导率的增加是含钪锆过饱和固溶体的分解形成弥散型的复相结构。

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  • The present invention relates to a tanshinone solid dispersion and its preparation method.

    本发明提供了一种丹参酮固体分散物及其制备方法。

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  • Methods: HPMC and stearic acid were used to prepare melatonin controlled-release bilayer tablets by application of solid dispersion method and double compression technology.

    方法:以hpmc、硬脂酸为骨架材料,采用固体分散技术和双层压片工艺,制备褪黑素双层控释片。

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  • Objective To prepare adefovir dipivoxil solid dispersion from poorly-soluble adefovir dipivoxil so as to improve its dissolution rate in vitro.

    目的 将难溶性药物阿德福韦酯制备成固体分散体,以增加体外溶出度。

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  • Results: The in vitro dissolution rates of ISDN solid dispersion were faster than ISDN.

    结果:固体分散体能加快药物的溶出速率,最佳比例为1∶7。

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  • Methods: the solid dispersion was prepared by solvent method. The solubility, the dissolution rate and the derivative thermogravimetry (DTG) were determined.

    方法:采用溶剂法制备固体分散体,进行溶解度、溶出速率测定,导数热重分析(DTG)。

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  • The results of DSC and PXRD showed that the quercetin in solid dispersion was amorphous form.

    热差分析及粉末X衍射结果表明固体分散体中槲皮素呈非结晶形式;

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  • Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method in examining the dispersivity of solid dispersion.

    结论:拉曼光谱法快速、直接、对样品无损伤,是一种新的理想的检查固体分散体分散性的方法。

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  • Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method in examining the dispersivity of solid dispersion.

    结论:拉曼光谱法快速、直接、对样品无损伤,是一种新的理想的检查固体分散体分散性的方法。

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