Disclosed are compounds for SH2 domain binding inhibition.
披露是SH2结构域结合抑制化合物。
SHIP-1 is an SH2 domain containing inositol-5-phosphatase that appears to be a negative regulator of hematopoiesis.
是一个含有SH2结构域的肌醇5磷酸酶，在造血过程中起负调节作用。
These compounds are targeted for use as inhibitors of SH2 domain binding with a phosphoprotein, and are contemplated for use in a number of diseases including cancer.
这些化合物主要针对作为SH2结构与磷酸结合域抑制剂的使用，是在一个许多疾病，包括癌症的使用设想。
The compounds of the present invention may also be employed as inhibitors of other enzymes characterized with a phosphotyrosine binding region such as the SH2 domain.
本发明的化合物还可用作以磷酸酪氨酸结合区如SH 2结构域为特征的其它酶的抑制剂。
The compounds of the present invention may also be employed as inhibitors of other enzymes characterized with a phosphotyrosine binding region such as the SH2 domain.
本发明的化合物还可用作以磷酸酪氨酸结合区如SH 2结构域为特征的其它酶的抑制剂。
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