Although it is known that mutations in the CFTR gene cause the disease, variations in other genes between individuals with CF modify the severity of the disease.
虽然，囊性纤维跨膜通道调节因子基因（CFTR）突变是这种疾病的病因，但在患有CF的病人之间的不同基因的变异会改变这种疾病的严重度。
Conclusion: The R219K polymorphism of ABCA1 gene are associated with not only plasma lipid levels but also with severity of CHD.
结论：ABCA1基因R 2 19 K多态性不仅与血脂水平并与CHD发病及病情严重程度明显相关。
Conclusion: The R219K polymorphism of ABCA1 gene are associated with not only plasma lipid levels but also with severity of CHD.
结论：ABCA1基因R 2 19 K多态性不仅与血脂水平并与CHD发病及病情严重程度明显相关。
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